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[Turisteron治疗前列腺癌的IV期多中心临床试验初步结果]

[Initial results of a phase IV multicenter clinical trial of Turisteron in the treatment of prostate cancer].

作者信息

Guddat H M, Schnorr D, Zemke F

出版信息

Z Urol Nephrol. 1987 Mar;80(3):165-70.

PMID:3300098
Abstract

Turisteron proves to be a highly effective, poor in side effects, orally applicable estrogen preparation for the hormone therapy of the carcinoma of the prostate under the conditions of the routine practice. The cumulative 5-year survival rates of 197 patients observed of all categories of tumours (T1-4NxM0-1) were 66 +/- 10% and were depending upon the local growth of the tumour and upon the degree of metastasation between 81 +/- 18% and 47 +/- 42%. A discontinuation of the therapy due to strong side effects was necessary only in 4 cases (2.07%).

摘要

在常规临床实践条件下,Turisteron被证明是一种用于前列腺癌激素治疗的高效、副作用小且可口服的雌激素制剂。观察的197例各类肿瘤(T1 - 4NxM0 - 1)患者的累积5年生存率为66±10%,且取决于肿瘤的局部生长情况以及转移程度,在81±18%至47±42%之间。仅4例(2.07%)患者因强烈副作用而有必要中断治疗。

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