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[前列腺癌激素治疗中的肝损伤]

[Liver damage in hormone therapy of prostate cancer].

作者信息

Zade W, Schott H

出版信息

Z Urol Nephrol. 1987 Mar;80(3):177-9.

PMID:3604474
Abstract

The behaviour of the transaminases under contra-sexual initial treatment of the carcinoma of the prostate gland with Cytonal in contrast to Turisteron was compared. In these cases under the Cytonal therapy as an expression of the hepatotoxic side effects a double as high serum activity of the transaminase ALAT could be proved compared with the serum activity of the patients treated with Turisteron. Due to the good tolerability and the only insignificant hepatotoxic reactions Turisteron is well suited for the long-term treatment of the carcinoma of the prostate gland.

摘要

对比了用赛托那(Cytonal)与土瑞司特(Turisteron)对前列腺癌进行异性初次治疗时转氨酶的行为。在这些接受赛托那治疗的病例中,作为肝毒性副作用的一种表现,与接受土瑞司特治疗的患者血清活性相比,可证明转氨酶丙氨酸氨基转移酶(ALAT)的血清活性高出两倍。由于土瑞司特耐受性良好且肝毒性反应微不足道,它非常适合用于前列腺癌的长期治疗。

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