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恢复期表型 II:物质使用障碍恢复期个体的延迟折扣、自我报告生活质量与缓解状态之间的关系。

The phenotype of recovery II: The association between delay discounting, self-reported quality of life, and remission status among individuals in recovery from substance use disorders.

机构信息

Addiction Recovery Research Center.

Center for Transformative Research on Health Behaviors.

出版信息

Exp Clin Psychopharmacol. 2022 Feb;30(1):59-72. doi: 10.1037/pha0000389. Epub 2020 Oct 1.

DOI:10.1037/pha0000389
PMID:33001696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9843550/
Abstract

Quality of life (QOL) and delay discounting (preference for smaller, immediate rewards) are significantly associated with substance use status, severity, and treatment outcomes. Associations between delay discounting and QOL among individuals in recovery from substance use have not been investigated. In this 2-study investigation, using data collected from The International Quit & Recovery Registry, we examined the association between QOL, discounting rates, and remission status among individuals in recovery from SUD. Study 1 ( = 166) investigated the relationship between delay discounting and QOL among individuals in recovery from SUD. Study 2 ( = 282) aimed to validate and extend the results of Study 1 by assessing the association between the remission status, delay discounting, and QOL among individuals in recovery from alcohol use disorder (AUD). In both studies, delay discounting was a significant predictor of QOL domains of physical health, psychological, and environment even after controlling for age, gender, race, ethnicity, education, and days since last use. In Study 2, a mediation analysis using Hayes's methods revealed that the association between the remission status and QOL domains of physical health, psychological and environment were partially mediated by the discounting rates. The current study expands the generality of delay discounting and indicates that discounting rates predict QOL and remission status among individuals in recovery from substance use disorders. This finding corroborates the recent characterizations of delay discounting as a candidate behavioral marker of addiction and may help identify subgroups that require special treatment or unique interventions to overcome their addiction. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

摘要

生活质量 (QOL) 和延迟折扣 (偏好较小的、即时的奖励) 与物质使用状况、严重程度和治疗结果显著相关。在物质使用康复者中,延迟折扣和 QOL 之间的关联尚未得到研究。在这项 2 项研究中,我们使用了从国际戒烟和康复登记处收集的数据,研究了物质使用障碍康复者的 QOL、折扣率和缓解状态之间的关系。研究 1(n=166)调查了物质使用障碍康复者的延迟折扣与 QOL 之间的关系。研究 2(n=282)旨在通过评估酒精使用障碍康复者的缓解状态、延迟折扣和 QOL 之间的关系来验证和扩展研究 1 的结果。在这两项研究中,即使在控制了年龄、性别、种族、民族、教育程度和最后一次使用的天数后,延迟折扣仍是身体健康、心理和环境等 QOL 领域的显著预测因素。在研究 2 中,使用 Hayes 方法的中介分析表明,缓解状态与身体健康、心理和环境等 QOL 领域之间的关联部分是由折扣率中介的。本研究扩展了延迟折扣的普遍性,并表明折扣率可以预测物质使用障碍康复者的 QOL 和缓解状态。这一发现证实了最近将延迟折扣描述为成瘾的候选行为标志物的说法,并可能有助于识别需要特殊治疗或独特干预措施来克服成瘾的亚组。(PsycInfo 数据库记录(c)2022 APA,保留所有权利)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/6f108c7ec7d9/nihms-1852489-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/b5db51d62b8c/nihms-1852489-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/9dd6ffa64f50/nihms-1852489-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/6f108c7ec7d9/nihms-1852489-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/b5db51d62b8c/nihms-1852489-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/9dd6ffa64f50/nihms-1852489-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e381/9843550/6f108c7ec7d9/nihms-1852489-f0003.jpg

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