Clinical activity of axicabtagene ciloleucel in adult patients with Richter syndrome.
作者信息
Kittai Adam S, Bond David A, William Basem, Saad Ayman, Penza Sam, Efebera Yvonne, Larkin Karilyn, Wall Sarah A, Choe Hannah K, Bhatnagar Bhavana, Vasu Sumithira, Brammer Jonathan, Shindiapina Polina, Long Meixiao, Mims Alice, O'Donnell Lynn, Bhat Seema A, Rogers Kerry A, Woyach Jennifer A, Byrd John C, Jaglowski Samantha M
机构信息
Division of Hematology, Department of Internal Medicine.
Arthur G. James Comprehensive Cancer Center.
出版信息
Blood Adv. 2020 Oct 13;4(19):4648-4652. doi: 10.1182/bloodadvances.2020002783.
Abstract
摘要
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Blood. 2020 May 7;135(19):1650-1660. doi: 10.1182/blood.2019002936.
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Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib.抗 CD19 嵌合抗原受体 T 细胞疗法 Lisocabtagene Maraleucel 联合伊布替尼或阿卡替尼的抗肿瘤活性。
J Immunother. 2020 May;43(4):107-120. doi: 10.1097/CJI.0000000000000307.
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Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8 T cells and impede CAR T-cell efficacy.慢性淋巴细胞白血病细胞损害 CD8 T 细胞中的线粒体功能，从而阻碍嵌合抗原受体 T 细胞疗法的疗效。
Blood. 2019 Jul 4;134(1):44-58. doi: 10.1182/blood.2018885863. Epub 2019 May 10.
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ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells.ASTCT 细胞因子释放综合征和免疫效应细胞相关神经系统毒性的共识分级标准。
Biol Blood Marrow Transplant. 2019 Apr;25(4):625-638. doi: 10.1016/j.bbmt.2018.12.758. Epub 2018 Dec 25.
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Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma.Tisagenlecleucel 治疗成人复发或难治性弥漫性大 B 细胞淋巴瘤。
N Engl J Med. 2019 Jan 3;380(1):45-56. doi: 10.1056/NEJMoa1804980. Epub 2018 Dec 1.
6
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.慢性淋巴细胞白血病中 CD19 嵌合抗原受体 (CAR) T 细胞治疗应答和耐药的决定因素。
Nat Med. 2018 May;24(5):563-571. doi: 10.1038/s41591-018-0010-1. Epub 2018 Apr 30.
7
Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.阿基仑赛注射液嵌合抗原受体T细胞疗法治疗难治性大B细胞淋巴瘤
N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447. Epub 2017 Dec 10.
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Br J Haematol. 2018 Jan;180(2):259-266. doi: 10.1111/bjh.15035. Epub 2017 Nov 28.
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Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor-Modified T Cells After Failure of Ibrutinib.依鲁替尼治疗失败后，用CD19特异性嵌合抗原受体修饰的T细胞治疗慢性淋巴细胞白血病的持久分子缓解。
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Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia.伊布替尼可增强嵌合抗原受体T细胞在白血病中的植入及疗效。
Blood. 2016 Mar 3;127(9):1117-27. doi: 10.1182/blood-2015-11-679134. Epub 2016 Jan 26.
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