冻疮样皮损的血管内皮细胞和汗腺细胞中均存在 SARS-CoV-2 刺突蛋白。
SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion.
机构信息
Skin Cancer Center, Department of Dermatology, Ruhr-University Bochum, Bochum, Germany.
Department of Internal Medicine, Ruhr-University Bochum, Bochum, Germany.
出版信息
J Eur Acad Dermatol Venereol. 2021 Mar;35(3):e187-e189. doi: 10.1111/jdv.16970. Epub 2020 Dec 23.
Abstract
Data on SARS‐CoV‐2 detection in lesional skin is controversial. We report a PCR‐proven COVID‐19 patient with a chilblain‐like SARS‐CoV‐2 positive skin lesion. An 80‐year‐old woman presented to the emergency department at the End of March 2020. She reported an onset of fever (38.4 C°) several days before admission, along with cough and shortness of breath. RT‐PCR from a nasopharyngeal swab was positive for SARS‐CoV‐2. An X‐ray showed evidence for right‐sided pneumonic infiltrates.
摘要
有关 SARS-CoV-2 在皮损皮肤中检测的数据存在争议。我们报告了一例经 PCR 证实的 COVID-19 患者，其皮肤损伤表现为冻疮样，SARS-CoV-2 检测阳性。一名 80 岁女性于 2020 年 3 月底因发热（38.4°C）数天、咳嗽和呼吸急促到急诊就诊。鼻拭子的 RT-PCR 检测对 SARS-CoV-2 呈阳性。X 光片显示右侧肺部浸润性病变。
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