Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, PR China.
J Dermatolog Treat. 2022 May;33(3):1243-1251. doi: 10.1080/09546634.2020.1825614. Epub 2020 Oct 2.
The term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated abnormalities in elastic fibers, collagen fibrils, and other extracellular matrix (ECM) components. Changes in the expression of hormone receptors and hormone levels have also been hypothesized. Considering this new information, we reviewed successful treatments of SG and listed them in two tables. Our review found that topical treatments were relatively weak compared with laser and light treatment, with which the appearance of SR and SA can be significantly improved. Lasers combined with other modalities, such as additional energy devices and topical agents, were also proven effective, but more large-scale trials are necessary.
术语妊娠纹（SG）是指一种特别在怀孕期间出现的伸展纹（SD）。根据病变的成熟程度，SG 分为红纹（SR）和白纹（SA）。其发病机制尚不清楚；最近的研究表明弹性纤维、胶原纤维和其他细胞外基质（ECM）成分异常。激素受体和激素水平的变化也被假设存在。考虑到这一新信息，我们回顾了 SG 的成功治疗方法，并将其列在两个表中。我们的综述发现，与激光和光疗相比，局部治疗相对较弱，激光和光疗可以显著改善 SR 和 SA 的外观。联合其他模式的激光，如额外的能量设备和局部药物，也被证明是有效的，但还需要更多的大规模试验。
