Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Suite 2175, Miami, FL, 33136, USA.
Department of Dermatology, Prince Sattam Bin Abdulaziz University, Kharj, Saudi Arabia.
Am J Clin Dermatol. 2016 Jun;17(3):239-56. doi: 10.1007/s40257-016-0182-8.
Striae distensae (SD) are common dermatologic lesions that often arise as a result of rapid weight change, certain endocrine conditions, or prolonged exposure to steroids. SD initially present as raised edematous plaques (striae rubra), after which they become white and atrophic (striae alba) owing to local breakdown and reorganization of collagen and elastin. There currently exists no reliable treatment option, though numerous topical applications have been attempted. Lasers and light represent emerging noninvasive therapies that have demonstrated some success targeting vascular chromophores in striae rubra and stimulating collagen and elastin production in striae alba. An extensive literature review was performed to gather all available articles studying laser and light treatments for SD. Lasers and light can significantly improve the appearance of both striae rubra and striae alba. Generally, striae rubra are more responsive to therapy and can be treated successfully with a variety of lasers without major adverse effects. Fractional lasers exhibit the strongest results for striae alba repigmentation and collagen induction, and several other lasers produce temporary repigmentation. Lasers in combination with other modalities such as topical agents and additional energy devices have also demonstrated promising preliminary results; however, large comparative studies are necessary to validate these outcomes.
膨胀纹（SD）是常见的皮肤病变，通常是由于体重快速变化、某些内分泌疾病或长期暴露于类固醇引起的。SD 最初表现为凸起的水肿斑块（红色条纹），随后由于局部胶原和弹性蛋白的破坏和重组，它们变成白色和萎缩（白色条纹）。目前尚无可靠的治疗方法，尽管已经尝试了许多局部应用。激光和光代表新兴的非侵入性治疗方法，已经证明它们在治疗红色条纹中的血管色素和刺激白色条纹中的胶原和弹性蛋白生成方面取得了一定的成功。进行了广泛的文献综述，以收集所有研究激光和光治疗 SD 的可用文章。激光和光可以显著改善红色条纹和白色条纹的外观。一般来说，红色条纹对治疗的反应更好，可以用多种激光成功治疗，而不会产生重大不良反应。分束激光对白色条纹的色素沉着和胶原诱导效果最强，其他几种激光也能产生暂时的色素沉着。激光与其他治疗方法（如局部制剂和其他能量设备）联合使用也显示出了有前途的初步结果；然而，需要进行大规模的比较研究来验证这些结果。
