对包括人半合成胰岛素在内的各种胰岛素制剂的迟发型过敏反应。

Delayed-type allergy against various insulin preparations including human semisynthetic insulin.

作者信息

Würzburger M I, Prelević G M, Despotović N, Vucković S, Brkić S D, Bozović M, Nastić-Mirić D

出版信息

Ann Allergy. 1987 Jul;59(1):44-7.

Abstract

The authors present a patient with delayed-type allergy against insulin preparations of different species including highly purified monocomponent insulin and human semisynthetic insulin. Positive results for cutaneous delayed-type hypersensitivity and for lymphocyte blastogenesis suggested a type IV immunopathogenic reaction. Intradermal tests performed with various components of insulin preparations revealed delayed-type allergy to insulins of different species (bovine, porcine and human) but not to any of the other components.

摘要

作者报告了一名对包括高纯度单组分胰岛素和人半合成胰岛素在内的不同种类胰岛素制剂发生迟发型过敏的患者。皮肤迟发型超敏反应和淋巴细胞增殖反应呈阳性，提示为IV型免疫致病反应。用胰岛素制剂的各种成分进行的皮内试验显示，患者对不同种类（牛、猪和人）的胰岛素存在迟发型过敏，但对其他任何成分均无过敏反应。