Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California.
Cancer Discov. 2020 Oct;10(10):1442-1444. doi: 10.1158/2159-8290.CD-20-1087.
In this issue of , Pennycuick and colleagues comprehensively evaluate the immune contexture of progressive and regressive lesions in squamous pulmonary premalignancy. The authors dissect the molecular features of these lesions and the potential pathways of immune escape operative in progression to invasive cancer..
本期 ,Pennycuick 及其同事全面评估了鳞状肺前恶性病变中进行性和退行性病变的免疫结构。作者剖析了这些病变的分子特征以及在进展为浸润性癌过程中可能发生免疫逃逸的潜在途径。