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儿童和青少年哮喘:ControL'Asma 项目。

Asthma in children and adolescents: the ControL'Asma project.

机构信息

Pediatric Clinic, Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Department of Medicine, Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

出版信息

Acta Biomed. 2020 Sep 15;91(11-S):e2020002. doi: 10.23750/abm.v91i11-S.10295.

DOI:10.23750/abm.v91i11-S.10295
PMID:33004772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023065/
Abstract

The control of asthma is the objective of asthma management. However, it is difficult to obtain in clinical practice. The Italian Society of Allergy and Clinical Immunology promoted the nationwide project "ControL'Asma" to investigate the real situation in a group of children and adolescents with asthma. The preliminary outcomes demonstrated that many asthmatic subjects do not achieve adequate asthma control. Moreover, asthma in Italian children and adolescents was usually more frequent in males, had an early onset and allergic phenotype with very frequent rhinitis comorbidity, uncontrolled and partly controlled asthma affected about the half of subjects. However, this project suggested that the assessment of asthma symptom perception by VAS could be a reliable tool in the asthma management.

摘要

哮喘的控制是哮喘管理的目标。然而,在临床实践中很难实现。意大利变态反应和临床免疫学学会(SIAI)发起了一项全国性的项目“ControL'Asma”,旨在调查一组哮喘儿童和青少年的真实情况。初步结果表明,许多哮喘患者并未达到足够的哮喘控制。此外,意大利儿童和青少年哮喘通常在男性中更为常见,发病较早,具有过敏表型,常伴有鼻炎共病,未得到控制和部分控制的哮喘影响了约一半的患者。然而,该项目表明,通过 VAS 评估哮喘症状感知可能是哮喘管理中的一种可靠工具。

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本文引用的文献

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Allergic Endotypes and Phenotypes of Asthma.哮喘的过敏性内型和表型。
J Allergy Clin Immunol Pract. 2020 Feb;8(2):429-440. doi: 10.1016/j.jaip.2019.11.008.
2
Treatment Adherence in Adolescents with Asthma.青少年哮喘患者的治疗依从性
J Asthma Allergy. 2020 Jan 14;13:39-49. doi: 10.2147/JAA.S233268. eCollection 2020.
3
The role of atopy in asthma development and persistence.特应性在哮喘发病和持续中的作用。
Curr Opin Allergy Clin Immunol. 2020 Apr;20(2):131-137. doi: 10.1097/ACI.0000000000000627.
4
They just don't take their medicines: Reframing medication adherence in asthma from frustration to opportunity.他们就是不服药:将哮喘患者的服药依从性从挫折转变为机遇。
Pediatr Pulmonol. 2020 Mar;55(3):818-825. doi: 10.1002/ppul.24643. Epub 2020 Jan 15.
5
Age- and sex-dependent differences in patients with severe asthma included in the German Asthma Net cohort.德国哮喘网络队列研究中纳入的严重哮喘患者的年龄和性别依赖性差异。
Respir Med. 2020 Feb;162:105858. doi: 10.1016/j.rmed.2019.105858. Epub 2020 Jan 3.
6
A modern approach to identifying and characterizing child asthma and wheeze phenotypes based on clinical data.基于临床数据的现代儿童哮喘和喘息表型识别与特征描述方法。
PLoS One. 2019 Dec 30;14(12):e0227091. doi: 10.1371/journal.pone.0227091. eCollection 2019.
7
A primary care learning collaborative to improve office systems and clinical management of pediatric asthma.初级保健学习协作以改善儿科哮喘的办公系统和临床管理。
J Asthma. 2021 Mar;58(3):395-404. doi: 10.1080/02770903.2019.1702199. Epub 2019 Dec 14.
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From ARIA guidelines to the digital transformation of health in rhinitis and asthma multimorbidity.从变应性鼻炎和哮喘共病的ARIA指南到健康领域的数字化转型
Eur Respir J. 2019 Dec 4;54(6). doi: 10.1183/13993003.01023-2019. Print 2019 Dec.
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Immunomodulation in Pediatric Asthma.小儿哮喘中的免疫调节
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Targeted Therapy for Severe Asthma in Children and Adolescents: Current and Future Perspectives.儿童和青少年重度哮喘的靶向治疗:现状和未来展望。
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