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过敏反应有哪些新进展?

What is new in anaphylaxis?

作者信息

Martelli Alberto, Ippolito Rosario, Votto Martina, De Filippo Maria, Brambilla Ilaria, Calvani Mauro, Cardinale Fabio, Chiappini Elena, Duse Marzia, Manti Sara, Marseglia Gian Luigi, Caffarelli Carlo, Cravidi Claudio, Miraglia Del Giudice Michele, Tosca Maria Angela

机构信息

Department of Pediatrics, G. Salvini Hospital, Garbagnate Milanese, Milan - Italy.

Pediatric Clinic Department of Pediatrics, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy.

出版信息

Acta Biomed. 2020 Sep 15;91(11-S):e2020005. doi: 10.23750/abm.v91i11-S.10308.

Abstract

Available information suggests that anaphylaxis must be promptly recognized keeping in mind the airway patency, breathing (ventilation and respiration), circulation and mental status and treated. The first treatment is adrenaline. After successful treatment of an anaphylactic episode, attention must be paid to the prevention of early recurrences (biphasic anaphylaxis) and assessment of causes. Children should not be discharged before prescribing self-injectable adrenaline and explain how and under what circumstances it must be injected, An action plan must be communicated to their communities. Inform the school about potential reactions, how to prevent them and avoidance measures.

摘要

现有信息表明,必须迅速识别过敏反应,同时牢记气道通畅、呼吸(通气和呼吸)、循环及精神状态并进行治疗。首要治疗方法是肾上腺素。成功治疗过敏反应发作后,必须注意预防早期复发(双相性过敏反应)并评估病因。在开具自动注射肾上腺素并解释如何以及在何种情况下必须注射之前,儿童不应出院。必须向其社区传达一份行动计划。告知学校潜在反应、如何预防以及避免措施。

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本文引用的文献

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Reaction phenotypes in IgE-mediated food allergy and anaphylaxis.免疫球蛋白 E(IgE)介导的食物过敏和过敏反应的反应表型。
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Global Trends in Anaphylaxis Epidemiology and Clinical Implications.全球过敏反应流行病学趋势及其临床意义。
J Allergy Clin Immunol Pract. 2020 Apr;8(4):1169-1176. doi: 10.1016/j.jaip.2019.11.027. Epub 2019 Nov 28.

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