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变应性鼻结膜炎。

Allergic rhinoconjunctivitis.

机构信息

Department of Woman, Child and of General and Specialized Surgery. University of Campania "Luigi Vanvitelli" Naples, Italy.

epartment of Pediatrics, Bambino Gesù Children's Hospital, Rome, Italy.

出版信息

Acta Biomed. 2020 Sep 15;91(11-S):e2020007. doi: 10.23750/abm.v91i11-S.10310.

DOI:10.23750/abm.v91i11-S.10310
PMID:33004777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023069/
Abstract

Allergic rhinitis (AR) is induced by an IgE-mediated immune reaction after allergen exposure. The typical symptoms are itching, nasal discharge, sneezing and nasal obstruction. The diagnosis is based on the concordance between allergic symptoms and diagnostic tests. The skin prick test (SPT) is recommended as the "gold standard" method. First generation H1-antihistamines are widely used for treatment of AR. Intranasal glucocorticosteroids are well tolerated and can be used also in paediatric age. Allergic rhinitis cannot be considered as an isolated pathology. Other atopic diseases (allergic conjunctivitis, atopic eczema, asthma) are commonly associated.

摘要

变应性鼻炎(AR)是由过敏原暴露后 IgE 介导的免疫反应引起的。典型症状为瘙痒、鼻分泌物、打喷嚏和鼻塞。诊断基于过敏症状和诊断测试的一致性。皮肤点刺试验(SPT)被推荐为“金标准”方法。第一代 H1 抗组胺药广泛用于治疗 AR。鼻内糖皮质激素具有良好的耐受性,也可用于儿科年龄。变应性鼻炎不能被视为一种孤立的疾病。其他特应性疾病(过敏性结膜炎、特应性皮炎、哮喘)通常与之相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c57d/8023069/0d6d08cf1546/ACTA-91-07-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c57d/8023069/0d6d08cf1546/ACTA-91-07-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c57d/8023069/0d6d08cf1546/ACTA-91-07-g001.jpg

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Expert Opin Biol Ther. 2020 Jun;20(6):609-619. doi: 10.1080/14712598.2020.1729350. Epub 2020 Feb 19.
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2019 ARIA Care pathways for allergen immunotherapy.2019ARIA 变应原免疫治疗护理路径。
Allergy. 2019 Nov;74(11):2087-2102. doi: 10.1111/all.13805. Epub 2019 Jul 15.
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Management of ocular allergy.眼过敏的管理。
南非学龄前儿童特应性皮炎与室外和室内空气污染来源的关联。
Int J Environ Res Public Health. 2024 Mar 11;21(3):326. doi: 10.3390/ijerph21030326.
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Validated allergen exposure chamber is plausible tool for the assessment of house dust mite-triggered allergic rhinitis.经验证的过敏原暴露室是评估屋尘螨引发的过敏性鼻炎的合理工具。
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Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules.对 8 种重组梯牧草分子的 IgE 致敏谱的诊断相关性。
Allergy. 2018 Mar;73(3):673-682. doi: 10.1111/all.13338. Epub 2017 Dec 14.
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Clinical practice recommendations for allergen-specific immunotherapy in children: the Italian consensus report.儿童变应原特异性免疫治疗的临床实践建议:意大利共识报告。
Ital J Pediatr. 2017 Jan 23;43(1):13. doi: 10.1186/s13052-016-0315-y.
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Recent Updates on the Systemic and Local Safety of Intranasal Steroids.鼻内用类固醇全身及局部安全性的最新进展
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Pediatr Allergy Immunol. 2016 Dec;27(8):795-803. doi: 10.1111/pai.12681.
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Clin Exp Allergy. 2016 Jun;46(6):785-92. doi: 10.1111/cea.12730.
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Emerging drugs for the treatment of perennial allergic rhinitis.治疗常年性变应性鼻炎的新兴药物
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