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中药对非ST段抬高型急性冠状动脉综合征的个体化疗效:基于循证目标达成量表的观察性研究方案

Individualized Efficiency of Traditional Chinese Medicine for Non-ST Segment Elevation Acute Coronary Syndrome: Study Protocol for Observational Research by the Evidence-Based Goal Attainment Scale.

作者信息

Shi Zhaofeng, Zhao Chen, Guan Manke, Wei Xuxu, Hu Jiayuan, Zhang Xiaoyu, Li Min, Shang Hongcai

机构信息

Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Evid Based Complement Alternat Med. 2020 Sep 14;2020:7653040. doi: 10.1155/2020/7653040. eCollection 2020.

Abstract

BACKGROUND

Non-ST segment elevation acute coronary syndrome has been one of the most serious diseases threatening human health. Long-term cardiac rehabilitation and secondary prevention is the essential method to control the recurrence and mortality of the disease. Traditional Chinese medicine has proved the efficiency on the treatment of non-ST segment elevation acute coronary syndrome, but there is a lack of appropriate methodological design to reflect the characteristics of individualized diagnosis and treatment of it. Therefore, this study used the evidenced-based Goal Attainment Scale to evaluate the clinical effectiveness of traditional Chinese medicine on the treatment of non-ST segment elevation acute coronary syndrome.

METHOD

This is observational research with the prospective feature. A total of 200 patients will be recruited and observed in the three months by telephone or door visit, collecting the individualized intervention of traditional Chinese medicine and evaluating through the method of evidence-based Goal Attainment Scale. Participants will be included according to the inclusion and exclusion criteria. Any reasons for loss to follow-up and adverse events will be recorded strictly. . The evidence-based Goal Attainment Scale provides a personalized method of evaluation based on the Goal Attainment Scale and combined with evidence-based medicine, which can better reflect the characteristics and superiority of individualized and dynamic intervention for traditional Chinese medicine on the long-term prevention and treatment of non-ST segment elevation acute coronary syndrome than other methods of design. It is of great significance to explore and promote this method of design in the future.

摘要

背景

非ST段抬高型急性冠状动脉综合征一直是威胁人类健康的最严重疾病之一。长期心脏康复和二级预防是控制该疾病复发和死亡率的重要方法。中医已被证明对非ST段抬高型急性冠状动脉综合征的治疗有效,但缺乏合适的方法设计来体现其个体化诊疗特点。因此,本研究采用循证目标达成量表评估中医治疗非ST段抬高型急性冠状动脉综合征的临床疗效。

方法

这是一项具有前瞻性的观察性研究。共招募200例患者,通过电话或上门访视进行为期三个月的观察,收集中医个体化干预措施,并采用循证目标达成量表法进行评估。将根据纳入和排除标准纳入参与者。严格记录任何失访原因和不良事件。循证目标达成量表基于目标达成量表并结合循证医学提供了一种个性化评估方法,与其他设计方法相比,它能更好地体现中医对非ST段抬高型急性冠状动脉综合征长期防治的个体化和动态干预的特点及优势。未来探索和推广这种设计方法具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd19/7509552/7c298151130e/ECAM2020-7653040.001.jpg

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