Velichko E V, Karaev Z O
Antibiot Med Biotekhnol. 1987 May;32(5):360-2.
Tetracycline hydrochloride, a broad spectrum antibiotic was studied with respect to its effect on Candida adhesion to epitheliocytes of the oral mucosa. The experiments on mice showed that administration of 0.1 per cent solution of the antibiotic to the animals for 4 days resulted in increasing the adhesive number (AN) and adhesion index (AI) up to 175 and 250 per cent respectively as compared to the control. After 3 weeks of the antibiotic use the AN and AI amounted to 220 and 350 per cent respectively as compared to the control.
对盐酸四环素这种广谱抗生素进行了研究，考察其对念珠菌黏附于口腔黏膜上皮细胞的影响。对小鼠的实验表明，给动物施用0.1%的抗生素溶液，持续4天，与对照组相比，黏附数量（AN）和黏附指数（AI）分别增加到175%和250%。在使用抗生素3周后，与对照组相比，AN和AI分别达到220%和350%。
