Karaev Z O, Velichko E V, Bykov V L
Zh Mikrobiol Epidemiol Immunobiol. 1986 Jul(7):59-61.
The adhesion of fungi belonging to the genus Candida to the epithelial cells of the mouth cavity reached its maximum at pH 6.2-7.0. The process of adhesion had similar dynamics at temperatures of 37 degrees, 28 degrees and 25 degrees C, but the adhesive activity decreased 2 times when temperature dropped from 37 degrees to 25 degrees and 4 times when temperature dropped to 4 degrees C. The introduction of the ions Ca2+ (1 and 10 mM) and Mg2+ (10 mM) led to the increase of adhesion by 80, 100 and 24% respectively. The heating of the fungal cells at 100 degrees C (for 1 hour) and at 63 degrees C (for 2 hours) decreased adhesion to 8 and 24% respectively, and treatment with formaldehyde (for 24 hours) decreased adhesion to 70% of that observed in experiments with live Candida cells.
念珠菌属真菌对口腔上皮细胞的黏附在pH 6.2 - 7.0时达到最大值。在37℃、28℃和25℃的温度下，黏附过程具有相似的动力学，但当温度从37℃降至25℃时，黏附活性降低2倍，当温度降至4℃时，黏附活性降低4倍。引入Ca2+（1和10 mM）和Mg2+（10 mM）离子分别使黏附增加80%、100%和24%。将真菌细胞在100℃加热1小时和在63℃加热2小时后，黏附分别降至8%和24%，用甲醛处理24小时后，黏附降至活念珠菌细胞实验中观察到的70%。
