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非妊娠健康患者特发性双侧卵巢静脉血栓形成:一例报告并文献复习

Idiopathic Bilateral Ovarian Vein Thrombosis in a Non-Pregnant Healthy Patient: A Case Report and Review of the Literature.

作者信息

Basit Abdul, Kaur Pushpinder, Villanueva Diana M, Tahir Muhammad, Sonnenschine Mark

机构信息

Internal Medicine, Coney Island Hospital, Brooklyn, USA.

Pathology, Case Western Reserve University School of Medicine, Cleveland, USA.

出版信息

Cureus. 2020 Aug 29;12(8):e10111. doi: 10.7759/cureus.10111.

DOI:10.7759/cureus.10111
PMID:33005529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7523547/
Abstract

Ovarian vein thrombosis (OVT) is a potentially life-threatening condition, and it is typically related to the peripartum period; however, it is also associated with pelvic inflammatory disease, recent pelvic or abdominal surgery, inflammatory bowel disease, thrombophilia, malignancy, and sepsis. Idiopathic isolated OVT is rare and is usually presented as case reports in the medical literature. In this report, we present a case of bilateral OVT in a postmenopausal female with no identifiable risk factors and normal coagulation profile workup to highlight the importance of considering it as a differential diagnosis in female patients presenting with abdominal pain. Early identification can prevent potentially life-threatening complications. Management is often conservative, and the choice of anticoagulation is based on the patient's medical conditions. In this particular scenario, the patient was managed with low molecular weight heparin (LMWH) and transitioned to direct oral anticoagulant (DOAC) before discharge.

摘要

卵巢静脉血栓形成(OVT)是一种潜在的危及生命的疾病,通常与围产期有关;然而,它也与盆腔炎性疾病、近期盆腔或腹部手术、炎症性肠病、血栓形成倾向、恶性肿瘤和败血症有关。特发性孤立性OVT很少见,在医学文献中通常以病例报告的形式呈现。在本报告中,我们介绍了一例绝经后女性双侧OVT病例,该患者没有可识别的危险因素且凝血指标检查正常,以强调在出现腹痛的女性患者中将其作为鉴别诊断的重要性。早期识别可预防潜在的危及生命的并发症。治疗通常是保守的,抗凝药物的选择基于患者的病情。在这种特殊情况下,患者接受了低分子量肝素(LMWH)治疗,并在出院前改用直接口服抗凝剂(DOAC)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1f/7523547/f82e77ef718e/cureus-0012-00000010111-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1f/7523547/86c95925e2c5/cureus-0012-00000010111-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1f/7523547/f82e77ef718e/cureus-0012-00000010111-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1f/7523547/86c95925e2c5/cureus-0012-00000010111-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1f/7523547/f82e77ef718e/cureus-0012-00000010111-i02.jpg

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Idiopathic Left Ovarian Vein Thrombosis.特发性左侧卵巢静脉血栓形成。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620947257. doi: 10.1177/2324709620947257.
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The challenges of diagnosing idiopathic ovarian vein thrombosis: Case report.特发性卵巢静脉血栓形成的诊断挑战:病例报告
Int J Surg Case Rep. 2019;60:63-65. doi: 10.1016/j.ijscr.2019.04.039. Epub 2019 May 3.
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Idiopathic ovarian vein thrombosis: a rare cause of abdominal pain.特发性卵巢静脉血栓形成:腹痛的罕见原因。
Am J Emerg Med. 2016 May;34(5):935.e1-2. doi: 10.1016/j.ajem.2015.09.022. Epub 2015 Sep 21.
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Idiopathic ovarian vein thrombosis in a nonperipartum patient.非围产期患者的特发性卵巢静脉血栓形成
Obstet Gynecol. 2015 Jun;125(6):1468-1470. doi: 10.1097/AOG.0000000000000648.
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Ovarian vein thrombosis in the nonpregnant woman: an overlooked diagnosis.非妊娠女性的卵巢静脉血栓形成:一种被忽视的诊断。
Ther Adv Hematol. 2012 Oct;3(5):325-8. doi: 10.1177/2040620712450887.
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Aust N Z J Obstet Gynaecol. 2010 Jun;50(3):299-301. doi: 10.1111/j.1479-828X.2010.01159.x.
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Ovarian vein thrombosis: a rare cause of abdominal pain outside the peripartum period.卵巢静脉血栓形成:围产期外腹痛的罕见原因。
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