Bannoura Sami, Barada Kassem, Sinno Sara, Boulos Fouad, Chakhachiro Zaher
Pathology and Laboratory Medicine Department, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El Solh, Beirut, 110-72020, Lebanon.
Department of Medicine, Gastroenterology Division, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El Solh, Beirut, 110-72020, Lebanon.
IDCases. 2020 Jul 25;22:e00925. doi: 10.1016/j.idcr.2020.e00925. eCollection 2020.
and co-infection has been reported to occur in a variety of sites in immunocompromised patients. To our knowledge, few cases of such co-infection have been reported to occur in the esophagus. We report a case of a 60-year-old woman who was maintained on immunosuppressive therapy for a presumed diagnosis of pemphigus vulgaris, who presented with odynophagia. Investigations revealed ulcerative esophagitis caused by both HSV and CMV. The patient was treated with valganciclovir with full recovery. We also present the results of various studies on patients with similar presentation particularly those caused by HSV and CMV co-infection.
据报道，免疫功能低下患者的多种部位会发生合并感染。据我们所知，很少有这种合并感染发生在食管的病例报告。我们报告一例60岁女性，因疑似寻常型天疱疮接受免疫抑制治疗，出现吞咽痛。检查发现由单纯疱疹病毒（HSV）和巨细胞病毒（CMV）引起的溃疡性食管炎。该患者接受缬更昔洛韦治疗后完全康复。我们还展示了对有类似表现患者的各种研究结果，特别是那些由HSV和CMV合并感染引起的患者。
