Adodina L V, Guvakova T V, Filiushina E E, Shmerling M D
Arkh Anat Gistol Embriol. 1987 Apr;92(4):78-86.
In hibernated ground squirrel (Citellus erythrogenys) during various periods of hibernation morphological changes in organs participating in insurance of energoplastic homeostasis (liver, endocrine part of the pancreas) have been followed. At the beginning of hibernation certain signs of functional strain in the liver are observed-shortening and swelling of the endoplasmic reticulum (ER) canaliculi, decreases of glycogen resources and activation of the lysosomal apparatus, as well as certain features demonstrating its decreased activity--shortening cisterns in the Golgi complex, poorly manifested granular ER, tightening of mitochondrial matrix. At a deep hibernation, the signs of strain disappear, ultrastructure of hepatocytes corresponds to a new lower level of functioning in comparison to that in the active state and at the beginning of hibernation. During these periods the structure of endocrine cells in the pancreas demonstrates certain changes in the character of functioning of the cells. Ultrastructural transformations in the liver and endocrine part of the pancreas in the ground squirrel are mutually correlated.
在冬眠不同阶段的冬眠地松鼠(红腹黄鼠)中,对参与能量动态平衡维持的器官(肝脏、胰腺内分泌部分)的形态变化进行了跟踪研究。在冬眠开始时,观察到肝脏出现某些功能应激迹象——内质网(ER)小管缩短和肿胀、糖原储备减少以及溶酶体装置激活,同时还有一些表明其活性降低的特征——高尔基复合体中的扁平囊缩短、粗面内质网表现不佳、线粒体基质紧缩。在深度冬眠时,应激迹象消失,与活跃状态及冬眠开始时相比,肝细胞的超微结构对应于一个新的较低功能水平。在这些时期,胰腺内分泌细胞的结构显示出细胞功能特征的某些变化。地松鼠肝脏和胰腺内分泌部分的超微结构变化相互关联。