Department of Physiology, R.D Gardi Medical College, Ujjain, Madhya Pradesh, India.
Center for Brain and Cognition, UC San Diego, San Diego, USA.
J Basic Clin Physiol Pharmacol. 2020 Oct 5;32(2):19-23. doi: 10.1515/jbcpp-2020-0019.
Electrical stimulation of the vestibular system (VeNS) has been shown to improve Insomnia Severity Index (ISI) when delivered during sleep. We hypothesize that repeated electrical vestibular stimulation, when delivered prior to sleep onset, will improve ISI scores. The primary aim of this study was to assess the effect that VeNS had on ISI scores when delivered prior to sleep onset. A secondary aim was to provide initial data indicating "length of time to effect" that will allow more appropriate design of a larger randomized control trial (RCT).
The present study was an experimental study (pre and post without control). The participants acted as self-controls. After recording the baseline values, electrical vestibular nerve stimulation was administered as intervention once in a day for 30 min, 1 h prior to sleep onset using ML1000 device (Neurovalens, UK) for 14 days.
There was significant decrease in the ISI scores followed by the electrical vestibular nerve stimulation. Further, participants reported a significant increase in well-rested sleep post the intervention period.
This study supports our hypothesis that VeNS has a positive impact on ISI scores when delivered on a regular basis prior to sleep onset.
已有研究表明，在睡眠期间对前庭系统（VeNS）进行电刺激可以改善失眠严重程度指数（ISI）。我们假设，在睡前反复进行电前庭刺激将改善 ISI 评分。本研究的主要目的是评估 VeNS 在睡前给予时对 ISI 评分的影响。次要目的是提供表明“起效时间”的初步数据，以便更恰当地设计更大规模的随机对照试验（RCT）。
本研究为实验研究（无对照的前后研究）。参与者作为自身对照。记录基线值后，使用 ML1000 设备（Neurovalens，英国）在睡前 1 小时内每天进行一次 30 分钟的电前庭神经刺激，共 14 天。
电前庭神经刺激后，ISI 评分显著下降。此外，参与者报告在干预后睡眠质量显著提高。
这项研究支持我们的假设，即 VeNS 在睡前定期给予时对 ISI 评分有积极影响。
