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自膨式金属支架置入治疗梗阻性结肠癌的近期疗效:一项回顾性队列研究。

Short-term outcomes after self-expandable metal stent insertion for obstructing colon cancer: a retrospective cohort study.

机构信息

From the Department of Surgery/General Surgery, King Saud University, Riyadh, Saudi Arabia.

From the Department of Internal Medicine/Gastroenterology, King Saud University, Riyadh, Saudi Arabia.

出版信息

Ann Saudi Med. 2020 Sep-Oct;40(5):403-407. doi: 10.5144/0256-4947.2020.403. Epub 2020 Oct 1.

Abstract

BACKGROUND

Self-expanding metal stents (SEMS) are used as a bridge to surgery for colon cancer patients as an alternative to emergency surgery. Currently, there is a paucity of literature from Saudi Arabia on the preoperative usage of SEMS.

OBJECTIVE

Determine whether SEMS are associated with a higher rate of complications.

DESIGN

Retrospective cohort study SETTINGS: Tertiary care hospital in Saudi Arabia.

PATIENTS AND METHODS

In patients diagnosed with obstructing colon cancer, up-front surgical resection was compared with insertion of SEMS followed by surgical resection between the years 2009 and 2013.

MAIN OUTCOME MEASURES

Rate of stent-related short-term complications. Secondary endpoint, postoperative complications.

SAMPLE SIZE

RESULTS

Twenty-four (36.9%) patients underwent SEMS placement; 41 (63.1%) underwent primary surgery. The median (interquartile range) hospital stay was significantly higher among the SEMS group (13 [8.5] days versus 7 [3] days in the primary surgery group, <.001). Five patients (20.8%) in the SEMS group developed complications: 2 (8.3%) perforations, 2 (8.3%) obstructions, and 1 (4.2%) stent migrations.

CONCLUSION

SEMS is associated with longer hospital stays and short-term serious complications. Further research should be conducted, preferably with a larger sample size.

LIMITATIONS

Retrospective design, small sample size.

CONFLICT OF INTEREST

None.

摘要

背景

自膨式金属支架(SEMS)可用作结肠癌患者手术的桥梁,作为急诊手术的替代方案。目前,沙特阿拉伯关于 SEMS 术前应用的文献很少。

目的

确定 SEMS 是否与更高的并发症发生率相关。

设计

回顾性队列研究

设置

沙特阿拉伯的一家三级护理医院。

患者和方法

在诊断为梗阻性结肠癌的患者中,比较了 2009 年至 2013 年间直接进行手术切除与插入 SEMS 后再进行手术切除的情况。

主要观察指标

支架相关短期并发症的发生率。次要终点为术后并发症。

样本量

65。

结果

24 例(36.9%)患者接受了 SEMS 放置;41 例(63.1%)患者接受了初次手术。SEMS 组的中位(四分位距)住院时间明显更长(13[8.5]天与初次手术组的 7[3]天,<.001)。SEMS 组中有 5 例(20.8%)患者出现并发症:2 例(8.3%)穿孔,2 例(8.3%)梗阻和 1 例(4.2%)支架移位。

结论

SEMS 与较长的住院时间和短期严重并发症相关。应进行进一步的研究,最好是采用更大的样本量。

局限性

回顾性设计,样本量小。

利益冲突

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fd/7532057/b579e81e8afc/0256-4947.2020.403-fig1.jpg

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