Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
作者信息
Martin Alicia R, Gignoux Christopher R, Walters Raymond K, Wojcik Genevieve L, Neale Benjamin M, Gravel Simon, Daly Mark J, Bustamante Carlos D, Kenny Eimear E
出版信息
Am J Hum Genet. 2020 Oct 1;107(4):788-789. doi: 10.1016/j.ajhg.2020.08.020.
Abstract
摘要
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本文引用的文献
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Negative selection on complex traits limits phenotype prediction accuracy between populations.复杂性状的负选择限制了不同人群之间的表型预测准确性。
Am J Hum Genet. 2021 Apr 1;108(4):620-631. doi: 10.1016/j.ajhg.2021.02.013. Epub 2021 Mar 9.
2
Lessons Learned from Bugs in Models of Human History.从人类历史模型中的错误中吸取的教训。
Am J Hum Genet. 2020 Oct 1;107(4):583-588. doi: 10.1016/j.ajhg.2020.08.017.
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Polygenic Scores for Height in Admixed Populations.混合人群中身高的多基因评分
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Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations.理论和实证量化多基因评分在祖先差异人群中的准确性。
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A community-maintained standard library of population genetic models.一个社区维护的种群遗传模型标准库。
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