Referral Center for Eating Disorder, Hospices Civils de Lyon, F-69677 Bron, France.
Referral Center for Eating Disorder, Hospices Civils de Lyon, F-69677 Bron, France; Univ Lyon, CarMeN laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1, F-69310 Pierre-Benite, France; Departement of Pediatric Nutrition, Hôpital Femme Mère Enfant, Univ Lyon, Hospice Civil de Lyon, Bron, F-69002, France.
Psychiatry Res. 2020 Nov;293:113472. doi: 10.1016/j.psychres.2020.113472. Epub 2020 Sep 23.
The contribution of an addictive process to anorexia nervosa (AN) is an area of growing interest. Yet, little is known about how the food addiction concept (FA) may be of interest in understanding AN. This study investigates prevalence of FA diagnostic and its association with markers of severity in individuals with AN. We conducted a retrospective study in a sample of 73 patients with AN. We assessed FA with the Yale Food Addiction Scale 2.0, depressive and anxiety disorders, impulsivity (Beck Depression Inventory, STAI, BIS-11) and eating behavior (BITE, EDE-Q). Prevalence of FA in our sample was 47%. FA was significantly associated and positively correlated with the binge-eating/purging subtype of AN, higher levels of depression, anxiety and greater eating psychopathology. FA was not associated with level of impulsivity nor leptin and IGF-1 blood levels. The relationship between FA severity and AN severity was mediated by the severity of binge eating behaviors. Our results suggest that the presence of FA may represent a more severe variant of AN. Longitudinal studies are needed to better understand the etiologic process between FA and AN.
成瘾过程对神经性厌食症(AN)的影响是一个日益受到关注的领域。然而,人们对食物成瘾概念(FA)如何有助于理解 AN 知之甚少。本研究调查了 FA 诊断的患病率及其与 AN 患者严重程度标志物的相关性。我们对 73 名 AN 患者进行了回顾性研究。我们使用耶鲁食物成瘾量表 2.0 评估 FA,评估抑郁和焦虑障碍、冲动性(贝克抑郁量表、STAI、BIS-11)和饮食行为(BITE、EDE-Q)。我们样本中 FA 的患病率为 47%。FA 与 AN 的暴食/清除亚型显著相关且呈正相关,与更高水平的抑郁、焦虑和更大的饮食心理病理相关。FA 与冲动性水平或瘦素和 IGF-1 血水平无关。FA 严重程度与 AN 严重程度之间的关系受暴食行为严重程度的中介。我们的结果表明,FA 的存在可能代表了 AN 的一种更严重的变异。需要进行纵向研究以更好地了解 FA 和 AN 之间的病因过程。