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Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults.多巴胺 D2 受体基因遗传变异与青年期有害饮酒相关和中介因素。
Addict Biol. 2023 Mar;28(3):e13269. doi: 10.1111/adb.13269.
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Food addiction in anorexia nervosa: Implications for the understanding of crossover diagnosis.神经性厌食症中的食物成瘾:对跨诊断理解的影响。
Eur Eat Disord Rev. 2022 May;30(3):278-288. doi: 10.1002/erv.2897. Epub 2022 Mar 20.
4
Food addiction and lifetime alcohol and illicit drugs use in specific eating disorders.特定进食障碍与食物成瘾和终生酒精及非法药物使用的关系。
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The Impact of Alcohol and Other Substance Use Disorders on Mortality in Patients With Eating Disorders: A Nationwide Register-Based Retrospective Cohort Study.酒精和其他物质使用障碍对饮食失调患者死亡率的影响:一项基于全国登记的回顾性队列研究。
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6
Clustering Treatment Outcomes in Women with Gambling Disorder.聚类女性赌博障碍患者的治疗结局。
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7
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Change in decision-making skills and risk for eating disorders in adolescence: A population-based study.青少年决策技能变化与饮食失调风险:一项基于人群的研究。
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10
FOOD ADDICTION AS A PROXY FOR ANOREXIA NERVOSA SEVERITY: NEW DATA BASED ON THE YALE FOOD ADDICTION SCALE 2.0.食物成瘾作为神经性厌食严重程度的替代指标:基于耶鲁食物成瘾量表 2.0 的新数据。
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食物成瘾和终身物质使用对饮食障碍治疗结果的影响。

The Role of Food Addiction and Lifetime Substance Use on Eating Disorder Treatment Outcomes.

机构信息

CIBER Fisiopatología Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Clinical Psychology Unit, L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge, 08907 Barcelona, Spain.

出版信息

Nutrients. 2023 Jun 27;15(13):2919. doi: 10.3390/nu15132919.

DOI:10.3390/nu15132919
PMID:37447246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10346594/
Abstract

Food addiction (FA) and substance use (SU) in eating disorders (ED) have been associated with a more dysfunctional clinical and psychopathological profile. However, their impact on treatment outcomes has been poorly explored. Therefore, this transdiagnostic study is aimed at examining whether the presence of FA and/or SU is associated with treatment outcomes in patients with different ED types. The results were not able to reveal significant differences in treatment outcomes between patients with and without FA and/or SU; however, the effect sizes suggest higher dropout rates in the group with both FA and SU. The predictive models of treatment outcomes showed different features associated with each group. High persistence (i.e., tendency to perseverance and inflexibility) was the personality trait most associated with poor treatment outcomes in patients without addictions. High harm avoidance and younger age at ED onset were the variables most related to poor outcomes in patients with FA or SU. Finally, in the group with both addictive behaviors (FA and SU), the younger patients presented the poorest outcomes. In conclusion, our results suggest that, regardless of presenting addictive behaviors, patients with ED may similarly benefit from treatment. However, it may be important to consider the differential predictors of each group that might guide certain treatment targets.

摘要

食物成瘾(FA)和物质使用(SU)与进食障碍(ED)有关,与更失调的临床和心理病理特征有关。然而,它们对治疗结果的影响还没有得到充分的探讨。因此,这项跨诊断研究旨在检查 FA 和/或 SU 的存在是否与不同 ED 类型患者的治疗结果有关。结果显示,在有 FA 和/或 SU 的患者和没有 FA 和/或 SU 的患者之间,治疗结果没有显著差异;然而,效果大小表明,同时存在 FA 和 SU 的患者组的辍学率更高。治疗结果的预测模型显示了与每个组相关的不同特征。高坚持性(即坚持和不灵活的倾向)是与无成瘾患者治疗结果不良最相关的人格特质。高伤害回避和 ED 发病年龄较小是 FA 或 SU 患者治疗结果不良的相关变量。最后,在同时存在两种成瘾行为(FA 和 SU)的患者中,年轻患者的治疗结果最差。总之,我们的研究结果表明,无论是否存在成瘾行为,ED 患者可能都能从治疗中同样受益。然而,考虑每个组的不同预测因素可能会指导某些治疗目标,这可能很重要。