Liu Lijia, Xu Haoxiang, Qi Feng, Wang Shangqian, Shadhu Kamleshsingh, Ramlagun-Mungur Dadhija, Wang Shui
Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
BMC Surg. 2020 Oct 2;20(1):218. doi: 10.1186/s12893-020-00883-9.
To observe cumulative morbidity of postoperative inguinal hernia (PIH) and identify risk factors associated with its development in patients who underwent retropubic radical prostatectomy (RRP), laparoscopic prostatectomy (LRP) or robotic assisted laparoscopic prostatectomy (RALP) operation.
From June 2009 to September 2016, 756 patients diagnosed with localized prostate cancer who had undergone RRP, LRP or RALP in our center were included in this study. Patients with PIH were retrospectively investigated in such factors as age, BMI, previous abdominal operations, diabetes mellitus history, hypertension history, prostate volume, previous hernia, operative methods, operative approach, preoperative Gleason, clinical T-stage, PLND situation, operative time, and estimated blood loss. Univariate and multivariate cox hazard regressions analysis were utilized to identify risk factors predisposing to PIH.
A total of 53 of 751(7.1%) patients developed PIH at a median follow-up period of 43 months. PIH rate in RRP was significantly higher compared to LRP and RALP group (RRP: 15.3%, LRP: 6.7%, RALP:1.9%, P = 0.038). Right side (69.8%) and indirect (88.8%) PIH were dominant type in hernia group. Univariate and multivariate cox hazard regressions analysis indicated that age and RRP approach were identified to be implicated to PIH [adjusted hazard ratio7.39(1.18-46.39), 2.93(95% CI 1.47-5.84)].
RRP technique and older age, especially patients over 80 years, are associated with higher incidence for PIH development. Appropriate prophylaxis during the operation should be evaluated for those in high-risk.
观察耻骨后根治性前列腺切除术(RRP)、腹腔镜前列腺切除术(LRP)或机器人辅助腹腔镜前列腺切除术(RALP)患者术后腹股沟疝(PIH)的累积发病率,并确定其发生的相关危险因素。
2009年6月至2016年9月,纳入在本中心接受RRP、LRP或RALP手术的756例诊断为局限性前列腺癌的患者。对PIH患者进行回顾性调查,内容包括年龄、体重指数、既往腹部手术史、糖尿病史、高血压史、前列腺体积、既往疝病史、手术方式、手术入路、术前Gleason评分、临床T分期、盆腔淋巴结清扫情况、手术时间和估计失血量。采用单因素和多因素cox风险回归分析确定PIH的易感危险因素。
751例患者中共有53例(7.1%)发生PIH,中位随访时间为43个月。RRP组的PIH发生率显著高于LRP组和RALP组(RRP:15.3%,LRP:6.7%,RALP:1.9%,P = 0.038)。疝组中右侧(69.8%)和间接性(88.8%)PIH为主要类型。单因素和多因素cox风险回归分析表明,年龄和RRP手术方式与PIH有关[调整后风险比7.39(1.18 - 46.39),2.93(95%可信区间1.47 - 5.84)]。
RRP技术和高龄,尤其是80岁以上患者,PIH发生率较高。应对高危患者在手术期间进行适当的预防评估。