Department of Urology, The First People's Hospital of Huzhou, #158, Square Road, Huzhou, 313000, China.
Department of Urology, Huzhou Key Laboratory of Precise Diagnosis and Treatment of Urinary Tumors, Huzhou, 313000, China.
BMC Urol. 2024 Jun 22;24(1):131. doi: 10.1186/s12894-024-01493-w.
The incidence of recurrent hernia after radical resection of prostate cancer is high, so this article discusses the incidence and risk factors of inguinal hernia after radical resection of prostate cancer.
This case control study was conducted in The First People's Hospital of Huzhou clinical data of 251 cases underwent radical resection of prostate cancer in this hospital from March 2019 to May 2021 were retrospectively analyzed. According to the occurrence of inguinal hernia, the subjects were divided into study group and control group, and the clinical data of each group were statistically analyzed, Multivariate Logistic analysis was performed to find independent influencing factors for predicting the occurrence of inguinal hernia. The Kaplan-Meier survival curve was drawn according to the occurrence and time of inguinal hernia.
The overall incidence of inguinal hernia after prostate cancer surgery was 14.7% (37/251), and the mean time was 8.58 ± 4.12 months. The average time of inguinal hernia in patients who received lymph node dissection was 7.61 ± 4.05 (month), and that in patients who did not receive lymph node dissection was 9.16 ± 4.15 (month), and there was no significant difference between them (P > 0.05). There were no statistically significant differences in the incidence of inguinal hernia with age, BMI, hypertension, diabetes, PSA, previous abdominal operations and operative approach (P > 0.05), but there were statistically significant differences with surgical method and pelvic lymph node dissection (P < 0.05). The incidence of pelvic lymph node dissection in the inguinal hernia group was 24.3% (14/57), which was significantly higher than that in the control group 11.8% (23/194). Logistic regression analysis showed that pelvic lymph node dissection was a risk factor for inguinal hernia after prostate cancer surgery (OR = 0.413, 95%Cl: 0.196-0.869, P = 0.02). Kaplan-Meier survival curve showed that the rate of inguinal hernia in the group receiving pelvic lymph node dissection was significantly higher than that in the control group (P < 0.05).
Pelvic lymph node dissection is a risk factor for inguinal hernia after radical resection of prostate cancer.
前列腺癌根治术后复发疝的发生率较高，因此本文探讨了前列腺癌根治术后腹股沟疝的发生率及危险因素。
本病例对照研究对 2019 年 3 月至 2021 年 5 月在湖州市第一人民医院行根治性前列腺切除术的 251 例患者的临床资料进行回顾性分析。根据腹股沟疝的发生情况，将患者分为研究组和对照组，对两组患者的临床资料进行统计学分析，采用多因素 Logistic 分析寻找预测腹股沟疝发生的独立影响因素。根据腹股沟疝的发生和时间绘制 Kaplan-Meier 生存曲线。
前列腺癌手术后腹股沟疝的总发生率为 14.7%（37/251），平均时间为 8.58±4.12 个月。行淋巴结清扫术的患者腹股沟疝的平均时间为 7.61±4.05（月），未行淋巴结清扫术的患者腹股沟疝的平均时间为 9.16±4.15（月），两者无统计学差异（P＞0.05）。年龄、BMI、高血压、糖尿病、PSA、既往腹部手术及手术方式与腹股沟疝的发生率无统计学差异（P＞0.05），但与手术方式及盆腔淋巴结清扫术有统计学差异（P＜0.05）。腹股沟疝组行盆腔淋巴结清扫术的发生率为 24.3%（14/57），明显高于对照组的 11.8%（23/194）。Logistic 回归分析显示，盆腔淋巴结清扫术是前列腺癌根治术后发生腹股沟疝的危险因素（OR=0.413，95%Cl：0.196-0.869，P=0.02）。Kaplan-Meier 生存曲线显示，行盆腔淋巴结清扫术组的腹股沟疝发生率明显高于对照组（P＜0.05）。
盆腔淋巴结清扫术是前列腺癌根治术后发生腹股沟疝的危险因素。
