Wilkinson D, Vowden P, Parkin A, Wiggins P A, Robinson P J, Kester R C
Br J Surg. 1987 Jun;74(6):516-9. doi: 10.1002/bjs.1800740633.
To evaluate isotope limb blood flow measurement in intermittent claudication we have assessed 58 non-diabetic patients comparing our new method with treadmill testing and Doppler assessment. Limb blood flow was applicable to all 58 patients; 25 patients were unable to walk on a treadmill and of the 33 who could 12 failed to walk for one minute, making a standard one minute exercise test inappropriate. In those patients who could perform exercise tests there was a significant correlation between maximum walking distance and limb blood flow (r = 0.35, P = 0.02). Resting, post-exercise and post-hyperaemic ankle-brachial systolic pressure indices bore no relationship to the maximum walking distance. Isotope limb blood flow measurement is reproducible (r = 0.97), can be applied to those patients who cannot walk on a treadmill and provides information about both legs. It correlated significantly with all the other tests and can be recommended for the minimally invasive assessment of intermittent claudication.
为了评估同位素肢体血流测量在间歇性跛行中的应用，我们对58例非糖尿病患者进行了评估，将我们的新方法与跑步机测试和多普勒评估进行了比较。肢体血流测量适用于所有58例患者；25例患者无法在跑步机上行走，在能够行走的33例患者中，有12例未能行走满1分钟，因此标准的1分钟运动测试并不适用。在那些能够进行运动测试的患者中，最大行走距离与肢体血流之间存在显著相关性（r = 0.35，P = 0.02）。静息、运动后和充血后踝臂收缩压指数与最大行走距离无关。同位素肢体血流测量具有可重复性（r = 0.97），可应用于无法在跑步机上行走的患者，并能提供双腿的信息。它与所有其他测试均有显著相关性，可推荐用于间歇性跛行的微创评估。
