A closer look at the mysterious HSD17B13.
作者信息
Dong X Charlie
机构信息
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
出版信息
J Lipid Res. 2020 Nov;61(11):1361-1362. doi: 10.1194/jlr.C120001160. Epub 2020 Oct 2.
Abstract
摘要
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本文引用的文献
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17-Beta Hydroxysteroid Dehydrogenase 13 Deficiency Does Not Protect Mice From Obesogenic Diet Injury.17-β 羟甾体脱氢酶 13 缺乏症不能保护小鼠免受致肥胖饮食的损伤。
Hepatology. 2021 May;73(5):1701-1716. doi: 10.1002/hep.31517. Epub 2021 Mar 16.
2
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort.全基因组关联研究非酒精性脂肪肝和肝脂肪性肝炎在组织学特征化队列中。
J Hepatol. 2020 Sep;73(3):505-515. doi: 10.1016/j.jhep.2020.04.003. Epub 2020 Apr 13.
3
Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.羟基类固醇17-β脱氢酶13变体增加磷脂并预防非酒精性脂肪性肝病中的纤维化。
JCI Insight. 2020 Mar 12;5(5):132158. doi: 10.1172/jci.insight.132158.
4
Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers.HSD17B13 基因变异可降低酒精滥用者发生肝硬化和肝细胞癌的风险。
Hepatology. 2020 Jul;72(1):88-102. doi: 10.1002/hep.30996. Epub 2020 May 20.
5
High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase-Lowering Effect of a HSD17B13 Variant.HSD17B13 变异可增加脂肪肝疾病风险并降低丙氨酸氨基转移酶。
Hepatology. 2020 Jan;71(1):56-66. doi: 10.1002/hep.30799. Epub 2019 Aug 9.
6
A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease.17β-羟甾体脱氢酶 13 变体可预防酒精性肝病中的肝细胞癌发展。
Hepatology. 2019 Jul;70(1):231-240. doi: 10.1002/hep.30623. Epub 2019 Apr 25.
7
17-Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease.17-β 羟甾类脱氢酶 13 是一种与非酒精性脂肪性肝病组织学特征相关的肝视黄醇脱氢酶。
Hepatology. 2019 Apr;69(4):1504-1519. doi: 10.1002/hep.30350. Epub 2019 Mar 5.
8
HCV-Associated Liver Fibrosis and HSD17B13.丙型肝炎病毒相关肝纤维化与17β-羟基类固醇脱氢酶13
N Engl J Med. 2018 Nov 8;379(19):1875-1876. doi: 10.1056/NEJMc1804638.
9
HSD17B13 and Chronic Liver Disease in Blacks and Hispanics.HSD17B13与黑人和西班牙裔人群的慢性肝病
N Engl J Med. 2018 Nov 8;379(19):1876-1877. doi: 10.1056/NEJMc1804027.
10
Role of HSD17B13 in the liver physiology and pathophysiology.HSD17B13 在肝脏生理学和病理生理学中的作用。
Mol Cell Endocrinol. 2019 Jun 1;489:119-125. doi: 10.1016/j.mce.2018.10.014. Epub 2018 Oct 24.
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