Brian C. Clark, Ph.D., Ohio Musculoskeletal and Neurological Institute, Ohio University, 250 Irvine Hall, Athens, OH 45701, 740-593-2354, Email:
J Nutr Health Aging. 2020;24(8):906-913. doi: 10.1007/s12603-020-1432-2.
To compare a composite measure of physical function that comprises locomotor and non-locomotor tests (i.e., the Mobility Battery Assessment (MBA)) with traditional measures of mobility (4-m usual gait speed (UGS), six-minute walk (6MW) gait speed, and short physical performance battery (SPPB) score) for assessing lower extremity function and discriminating community dwelling older adults with and without mobility limitations.
Cross-sectional, observational study.
Laboratory-based.
89 community-dwelling older adults (74.9±6.7).
Using principal component analysis we derived an MBA score for 89 community-dwelling older adults, and quantified 4-m UGS, 6MW gait speed, and SPPB score. The MBA score was based on five lab-based tests. We also quantified self-reported lower extremity function/mobility using the Neuro-QOL Lower Extremity Function-Mobility instrument. Based on this data a continuous score was derived and subjects were classified as "mobility limited" or "non-mobility limited". Correlations between the mobility measures and the Neuro-QOL score were calculated, and ROC curves were constructed to determine the AUC for the mobility measures ability to predict mobility limitations.
The MBA had the largest AUC (0.92) for discriminating mobility limitations and exhibited the strongest correlation (0.73) with the Neuro-QOL Lower Extremity Function-Mobility Scale. The worst performing predictors were the 4-meter UGS and stair climb power both with an AUC of 0.8 for discriminating mobility limitations, and a low correlation with Neuro-QOL Lower Extremity Function Scale of 0.39 and 0.46, respectively.
The MBA score moderately improves the magnitude of correlation and discrimination of mobility limitation in older adults than singular, standard tests of mobility.
将包含移动和非移动测试的综合身体功能指标(即移动电池评估 (MBA))与传统移动性测量方法(4 米常规步行速度 (UGS)、6 分钟步行 (6MW) 速度和简短身体表现电池 (SPPB) 评分)进行比较,以评估下肢功能并区分有和无移动限制的社区居住老年人。
横断面、观察性研究。
基于实验室。
89 名社区居住的老年人(74.9±6.7)。
我们使用主成分分析从 89 名社区居住的老年人中得出 MBA 评分,并量化了 4 米 UGS、6MW 步行速度和 SPPB 评分。MBA 评分基于五项实验室测试。我们还使用神经 QOL 下肢功能-移动性工具量化了自我报告的下肢功能/移动性。基于此数据得出了一个连续评分,并将受试者分为“移动受限”或“非移动受限”。计算了移动性测量与神经 QOL 评分之间的相关性,并构建了 ROC 曲线以确定移动性测量预测移动性限制的 AUC。
MBA 在区分移动性限制方面具有最大的 AUC(0.92),并且与神经 QOL 下肢功能-移动性量表的相关性最强(0.73)。表现最差的预测指标是 4 米 UGS 和楼梯攀爬功率,两者在区分移动性限制方面的 AUC 均为 0.8,与神经 QOL 下肢功能量表的相关性较低,分别为 0.39 和 0.46。
与单一的标准移动性测试相比,MBA 评分适度提高了对老年人移动性限制的相关性和区分度。