Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Department of Preventive Dental Science, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
Eur J Orthod. 2021 Apr 3;43(2):173-183. doi: 10.1093/ejo/cjaa051.
Malocclusion is a deviation from an anatomical norm that occurs in various populations. Evidence shows that it has physical and psychological implications as well as an influence on the patient's oral health-related quality of life (OHRQoL). Self-perception of oral health plays an important role in the understanding of malocclusion's influence on the quality of life. Malocclusion has been reported to impair a patient's function, appearance, interpersonal relationships and psychological well-being.
The aim of this study was to investigate whether adolescents aged between 11 and 18 years with malocclusion are at increased risk for having a high level of OHRQoL compared with those without malocclusion.
The Ovid Medline, Embase and Scopus databases were used to identify studies measuring the association between malocclusion and HRQoL.
Only cross-sectional studies were included, and the following inclusion criteria were used: subjects were systemically healthy; data were available for untreated malocclusion and OHRQoL; malocclusion was measured by Dental Aesthetic Index and Index of Orthodontic Treatment Needs; OHRQoL was assessed by Child Perception Questionnaire, Child Oral Health Impact Profile and Child Oral Health Impact Profile; and the paper was published in English.
Data were extracted by two independent reviewers. The Appraisal tool for Cross-Sectional Studies (AXIS) was used to establish the risk of bias, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence quality assessment tool was used to assess the impact of malocclusion on adolescents across studies.
The initial search yielded 530 papers. Eleven cross-sectional studies were included in the meta-analyses, and all data describing the relationship between malocclusion and OHRQoL were gathered via a structured questionnaire. Our results showed that malocclusion is linked to decreased OHRQoL in children and adolescents aged between 11 and 18 years in continuously analysed studies. However, in dichotomously analysed studies, it was shown that young people without malocclusion are linked to decreased OHRQoL.
Adolescents with severe levels of malocclusion might have among the worst levels of OHRQoL. The effects of malocclusion on OHRQoL were influenced by the age of the adolescents as well as by their culture and environment.
PROSPERO (CRD42020178657).
错颌畸形是一种发生在不同人群中的解剖学异常。有证据表明，它不仅具有生理和心理方面的影响，还会影响患者的口腔健康相关生活质量（OHRQoL）。对口腔健康的自我认知在理解错颌畸形对生活质量的影响方面起着重要作用。错颌畸形已被报道会损害患者的功能、容貌、人际关系和心理健康。
本研究旨在调查 11 至 18 岁的青少年中，错颌畸形患者与无错颌畸形患者相比，其 OHRQoL 是否更高，以此来评估错颌畸形患者是否存在更高的 OHRQoL 风险。
使用 Ovid Medline、Embase 和 Scopus 数据库来确定研究错颌畸形与 HRQoL 之间关联的研究。
仅纳入横断面研究，且纳入标准如下：研究对象为系统健康者；存在未经治疗的错颌畸形和 OHRQoL 数据；错颌畸形由 Dental Aesthetic Index 和 Index of Orthodontic Treatment Needs 测量；OHRQoL 由儿童感知问卷、儿童口腔健康影响量表和儿童口腔健康影响量表评估；研究论文以英文发表。
由两名独立的评审员提取数据。使用横断面研究评估工具（AXIS）来确定偏倚风险，并使用推荐评估、制定与评估分级（GRADE）证据质量评估工具来评估错颌畸形对各研究中青少年的影响。
最初的搜索产生了 530 篇论文。11 项横断面研究被纳入荟萃分析，所有描述错颌畸形与 OHRQoL 之间关系的数据都是通过结构化问卷收集的。我们的结果表明，在连续分析的研究中，11 至 18 岁的儿童和青少年中，错颌畸形与 OHRQoL 降低有关。然而，在二分类分析的研究中，无错颌畸形的年轻人与 OHRQoL 降低有关。
严重错颌畸形的青少年可能具有最差的 OHRQoL。错颌畸形对 OHRQoL 的影响受到青少年年龄、文化和环境的影响。
PROSPERO（CRD42020178657）。
