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AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia.美国胃肠病学会缺铁性贫血胃肠道评估临床实践指南
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2
Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease.炎症性肠病药物基因组学护照的预测疗效。
Aliment Pharmacol Ther. 2020 Jun;51(11):1105-1115. doi: 10.1111/apt.15762. Epub 2020 May 3.
3
AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary.美国胃肠病学会关于2019冠状病毒病大流行期间炎症性肠病管理的临床实践更新:专家评论
Gastroenterology. 2020 Jul;159(1):350-357. doi: 10.1053/j.gastro.2020.04.012. Epub 2020 Apr 10.
4
Comparative efficacy and safety of vedolizumab and infliximab in ulcerative colitis after failure of a first subcutaneous anti-TNF agent: a multicentre cohort study.在首支皮下抗 TNF 药物治疗失败后,比较维得利珠单抗和英夫利昔单抗治疗溃疡性结肠炎的疗效和安全性:一项多中心队列研究。
Aliment Pharmacol Ther. 2020 May;51(9):852-860. doi: 10.1111/apt.15680. Epub 2020 Mar 22.
5
Positioning Therapies in Ulcerative Colitis.溃疡性结肠炎的定位疗法
Clin Gastroenterol Hepatol. 2020 May;18(6):1280-1290.e1. doi: 10.1016/j.cgh.2020.01.017. Epub 2020 Jan 23.
6
HLADQA1*05 genotype predicts anti-drug antibody formation and loss of response during infliximab therapy for inflammatory bowel disease.HLADQA1*05 基因型可预测英夫利昔单抗治疗炎症性肠病时抗药物抗体的形成和应答丧失。
Aliment Pharmacol Ther. 2020 Feb;51(3):356-363. doi: 10.1111/apt.15563. Epub 2019 Oct 25.
7
DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD.牙医学博士视角:我对炎症性肠病治疗药物监测的看法。
Dig Dis Sci. 2019 Dec;64(12):3377-3381. doi: 10.1007/s10620-019-05796-z.
8
How, When, and for Whom Should We Perform Therapeutic Drug Monitoring?我们应该对谁、何时以及如何进行治疗药物监测?
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炎症性肠病管理中的“拨开云雾”。

Clearing of the Clouds in Inflammatory Bowel Disease Management.

机构信息

Florida State University College of Medicine, Tallahassee, FL, USA.

出版信息

Dig Dis Sci. 2020 Dec;65(12):3411-3417. doi: 10.1007/s10620-020-06635-2. Epub 2020 Oct 3.

DOI:10.1007/s10620-020-06635-2
PMID:33009978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7532337/
Abstract

The skies over inflammatory bowel disease care are beginning to clear. Success is being achieved in the management of inflammatory bowel disease due to ongoing research, new medications, and most significantly to the recognition of the importance of patient selection and the definition of remission. Five answered questions provide the basis for recent successes and forecast for clearing of the clouds. How do we classify the inflammatory bowel disease (IBD) patient? How do we select our medications to best match the patients' classifications? How do we monitor and manage medications during the course of care? How can we predict the likelihood of response to a selected medication? Besides medications and surgery, what else is needed for best care in 2020 and beyond? These questions are addressed in this communication.

摘要

炎症性肠病治疗的天空开始放晴。由于持续的研究、新的药物以及最重要的是对患者选择和缓解定义的重要性的认识,炎症性肠病的治疗取得了成功。五个回答问题为最近的成功提供了基础,并预测了云层的清除。我们如何对炎症性肠病(IBD)患者进行分类?我们如何选择药物以最好地匹配患者的分类?我们如何在治疗过程中监测和管理药物?我们如何预测对选定药物的反应可能性?除了药物和手术,2020 年及以后还需要什么才能获得最佳治疗?本通讯讨论了这些问题。