Florida State University College of Medicine, Tallahassee, FL, USA.
Dig Dis Sci. 2020 Dec;65(12):3411-3417. doi: 10.1007/s10620-020-06635-2. Epub 2020 Oct 3.
The skies over inflammatory bowel disease care are beginning to clear. Success is being achieved in the management of inflammatory bowel disease due to ongoing research, new medications, and most significantly to the recognition of the importance of patient selection and the definition of remission. Five answered questions provide the basis for recent successes and forecast for clearing of the clouds. How do we classify the inflammatory bowel disease (IBD) patient? How do we select our medications to best match the patients' classifications? How do we monitor and manage medications during the course of care? How can we predict the likelihood of response to a selected medication? Besides medications and surgery, what else is needed for best care in 2020 and beyond? These questions are addressed in this communication.
炎症性肠病治疗的天空开始放晴。由于持续的研究、新的药物以及最重要的是对患者选择和缓解定义的重要性的认识,炎症性肠病的治疗取得了成功。五个回答问题为最近的成功提供了基础,并预测了云层的清除。我们如何对炎症性肠病(IBD)患者进行分类?我们如何选择药物以最好地匹配患者的分类?我们如何在治疗过程中监测和管理药物?我们如何预测对选定药物的反应可能性?除了药物和手术,2020 年及以后还需要什么才能获得最佳治疗?本通讯讨论了这些问题。