Department of Geriatrics and Gerontology, Healthy Aging and Brain Wellness Program, Wake Forest Baptist Health, Sticht Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
Clin Geriatr Med. 2020 Nov;36(4):585-599. doi: 10.1016/j.cger.2020.06.003. Epub 2020 Aug 16.
Dementia incidence continues to rise in the United States and around the world. Although age is the single biggest risk factor for the development of dementia, it is not considered normal sequelae of aging. Although there has been little to no progress made in the past couple of decades in the treatment or cure of Alzheimer disease, there has been significant progress made in prevention. Single factors, such as hearing loss or cardiovascular risk factors, may increase the risk for cognitive decline. The opportunity to mitigate these risk factors provides an exciting new healthy aging approach to dementia prevention.
痴呆症的发病率在美国和世界各地持续上升。虽然年龄是痴呆症发展的最大单一风险因素，但它并不被认为是衰老的正常后果。尽管在过去几十年中，阿尔茨海默病的治疗或治愈方面几乎没有取得任何进展，但在预防方面已经取得了重大进展。单一因素，如听力损失或心血管危险因素，可能会增加认知能力下降的风险。减轻这些风险因素的机会为痴呆症预防提供了一种令人兴奋的新的健康老龄化方法。
