Faculty of Health, University of Canberra, Canberra, Australia.
Faculty of Health, University of Canberra, Canberra, Australia; Prehabilitation, Activity, Cancer, Exercise, Survivorship (PACES) Research Group, University of Canberra, Canberra, Australia.
Semin Oncol Nurs. 2020 Oct;36(5):151067. doi: 10.1016/j.soncn.2020.151067. Epub 2020 Sep 30.
This review sought to synthesize evidence examining the effect of exercise on prostate cancer patients undergoing androgen deprivation therapy (ADT).
A systematic literature search was conducted in electronic databases (CINAHL, MEDLINE, APA PsychINFO, Scopus, SPORTDiscus, and Cochrane Library) from their inception to March 31, 2020. Inclusion criteria were randomized controlled trials (RCTs) testing the effect of exercise on body composition, muscle strength and physical performance. Fourteen RCTs were included. Participant numbers within the individual RCTs ranged from 19 to 163 with heterogeneity in prostate cancer stage (localized and locally advanced diagnoses) with age of participants ranging from 43 to 90 years. The length of the interventions ranged from 12 weeks to 12 months, with the number of sessions per week ranging from 2 to 5. Resistance training intensity ranged from 60% to 90% 1RM and the aerobic training ranged from 60% to 90% HR.
Resistance training and sport (football) in the form of small sided games (SSGs) played an important role in preserving bone mineral density and lean mass as well as improving muscle strength and physical performance outcomes in men affected by prostate cancer undergoing ADT.
Multimodal exercise, including resistance exercise and activity that includes repeated sprints (SSGs), benefit the maintenance of bone mineral density and lean mass as well as increase strength and physical performance in men affected by prostate cancer undergoing ADT. Based on this evidence, nurses should coordinate timely referrals to qualified exercise physiologists or physiotherapist with expertise in cancer care.
本综述旨在综合考察运动对接受雄激素剥夺疗法（ADT）的前列腺癌患者的影响。
系统检索了电子数据库（CINAHL、MEDLINE、APA PsychINFO、Scopus、SPORTDiscus 和 Cochrane Library）从建库至 2020 年 3 月 31 日的文献。纳入标准为检验运动对身体成分、肌肉力量和身体机能影响的随机对照试验（RCT）。共纳入 14 项 RCT，参与者数量在各 RCT 中从 19 到 163 不等，前列腺癌分期（局部和局部晚期诊断）存在异质性，参与者年龄在 43 到 90 岁之间。干预时间从 12 周至 12 个月不等，每周治疗次数从 2 到 5 次不等。抗阻训练强度范围为 60%至 90%1RM，有氧训练强度范围为 60%至 90%HR。
抗阻训练和以小场足球（SSG）形式进行的运动对接受 ADT 的前列腺癌男性患者维持骨密度和瘦体重、改善肌肉力量和身体机能具有重要作用。
包括抗阻运动和包含多次冲刺的活动（SSG）在内的多模式运动有利于接受 ADT 的前列腺癌男性患者维持骨密度和瘦体重，提高力量和身体机能。根据这些证据，护士应该及时将患者转介给有资格的运动生理学家或物理治疗师，以获得癌症护理方面的专业知识。
