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膝关节单髁置换术后翻修风险与外科医生培训等级的相关性:国家关节登记数据的分析。

Association between surgeon training grade and the risk of revision following unicompartmental knee replacement: An analysis of National Joint Registry data.

机构信息

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, Southmead Hospital, Bristol, United Kingdom.

Faculty of Health, The University of Sheffield, Sheffield, United Kingdom.

出版信息

PLoS Med. 2024 Sep 10;21(9):e1004445. doi: 10.1371/journal.pmed.1004445. eCollection 2024 Sep.

DOI:10.1371/journal.pmed.1004445
PMID:39255266
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11386457/
Abstract

BACKGROUND

Unicompartmental knee replacements (UKRs) are performed by surgeons at various stages in training with varying levels of supervision, but we do not know if this is a safe practice with comparable outcomes to consultant-performed UKR. The aim of this study was to use registry data for England and Wales to investigate the association between surgeon grade (consultant, or trainee), the senior supervision of trainees (supervised by a scrubbed consultant, or not), and the risk of revision surgery following UKR.

METHODS AND FINDINGS

We conducted an observational study using prospectively collected data from the National Joint Registry for England and Wales (NJR). We included adult patients who underwent primary UKR for osteoarthritis (n = 106,206), recorded in the NJR between 2003 and 2019. Exposures were the grade of the operating surgeon (consultant, or trainee) and whether or not trainees were directly supervised by a consultant during the procedure (referred to as "supervised by a scrubbed consultant"). The primary outcome was all-cause revision surgery. The secondary outcome was the number of procedures revised for the following specific indications: aseptic loosening/lysis, infection, progression of osteoarthritis, unexplained pain, and instability. Flexible parametric survival models were adjusted for patient, operation, and healthcare setting factors. We included 106,206 UKRs in 91,626 patients, of which 4,382 (4.1%) procedures were performed by a trainee. The unadjusted cumulative probability of failure at 15 years was 17.13% (95% CI [16.44, 17.85]) for consultants, 16.42% (95% CI [14.09, 19.08]) for trainees overall, 15.98% (95% CI [13.36, 19.07]) for trainees supervised by a scrubbed consultant, and 17.32% (95% CI [13.24, 22.50]) for trainees not supervised by a scrubbed consultant. There was no association between surgeon grade and all-cause revision in either crude or adjusted models (adjusted HR = 1.01, 95% CI [0.90, 1.13]; p = 0.88). Trainees achieved comparable all-cause survival to consultants, regardless of the level of scrubbed consultant supervision (supervised: adjusted HR = 0.99, 95% CI [0.87, 1.14]; p = 0.94; unsupervised: adjusted HR = 1.03, 95% CI [0.87, 1.22]; p = 0.74). Limitations of this study relate to its observational design and include: the potential for nonrandom allocation of cases by consultants to trainees; residual confounding; and the use of the binary variable "surgeon grade," which does not capture variations in the level of experience between trainees.

CONCLUSIONS

This nationwide study of UKRs with over 16 years' follow up demonstrates that trainees within the current training system in England and Wales achieve comparable all-cause implant survival to consultants. These findings support the current methods by which surgeons in England and Wales are trained to perform UKR.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dea/11386457/9f080392ef92/pmed.1004445.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dea/11386457/dfe9379a6a3f/pmed.1004445.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dea/11386457/9f080392ef92/pmed.1004445.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dea/11386457/dfe9379a6a3f/pmed.1004445.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dea/11386457/9f080392ef92/pmed.1004445.g002.jpg
摘要

背景

单髁膝关节置换术(UKR)由处于不同培训阶段、接受不同程度监督的外科医生进行,但我们不知道这种做法是否安全,其结果是否与顾问进行的 UKR 可比。本研究的目的是利用英格兰和威尔士的注册数据,调查外科医生的级别(顾问或受训者)、受训者的高级监督情况(由擦洗顾问监督或未监督)与 UKR 后翻修手术风险之间的关系。

方法和发现

我们进行了一项观察性研究,使用英格兰和威尔士国家联合登记处(NJR)前瞻性收集的数据。我们纳入了 2003 年至 2019 年期间在 NJR 中记录的因骨关节炎接受初次 UKR 的成年患者(n=106206)。暴露因素为手术外科医生的级别(顾问或受训者)以及受训者在手术过程中是否由顾问直接监督(称为“由擦洗顾问监督”)。主要结局为所有原因的翻修手术。次要结局为以下特定指征的手术数量:无菌性松动/松解、感染、骨关节炎进展、不明原因疼痛和不稳定。灵活参数生存模型根据患者、手术和医疗保健环境因素进行了调整。我们纳入了 106206 例 UKR 中的 91626 名患者,其中 4382(4.1%)例由受训者进行。未经调整的 15 年累积失败概率为:顾问为 17.13%(95%CI[16.44,17.85]);受训者总体为 16.42%(95%CI[14.09,19.08]);由擦洗顾问监督的受训者为 15.98%(95%CI[13.36,19.07]);未由擦洗顾问监督的受训者为 17.32%(95%CI[13.24,22.50])。在未调整或调整模型中,外科医生的级别与所有原因的翻修均无关联(调整后的 HR=1.01,95%CI[0.90,1.13];p=0.88)。受训者与顾问一样,无论擦洗顾问监督水平如何,均能获得所有原因的生存(监督:调整后的 HR=0.99,95%CI[0.87,1.14];p=0.94;未监督:调整后的 HR=1.03,95%CI[0.87,1.22];p=0.74)。本研究的局限性在于其观察性设计,包括:顾问可能将病例非随机分配给受训者;残留混杂;以及使用“外科医生级别”的二进制变量,该变量无法捕捉受训者之间经验水平的差异。

结论

这项针对 UKR 的全国性研究随访时间超过 16 年,结果表明,英格兰和威尔士当前培训系统中的受训者获得了与顾问相当的全因植入物生存率。这些发现支持了目前英格兰和威尔士外科医生接受 UKR 培训的方法。

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Bone Joint J. 2022 Mar;104-B(3):341-351. doi: 10.1302/0301-620X.104B3.BJJ-2021-1389.R1.
3
Association between surgeon grade and implant survival following hip and knee replacement: a systematic review and meta-analysis.
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The effect of surgical approach in total knee replacement on outcomes. An analysis of 875,166 elective operations from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.全膝关节置换手术入路对手术结果的影响。对来自英格兰、威尔士、北爱尔兰和马恩岛国家关节注册中心的875,166例择期手术的分析。
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