Yu Jiade, Chen Jennifer K, Mowad Christen M, Reeder Margo, Hylwa Sara, Chisolm Sarah, Dunnick Cory A, Goldminz Ari M, Jacob Sharon E, Wu Peggy A, Zippin Jonathan, Atwater Amber Reck
Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Department of Dermatology, Stanford University School of Medicine, Redwood City, California.
J Am Acad Dermatol. 2021 Feb;84(2):486-494. doi: 10.1016/j.jaad.2020.09.074. Epub 2020 Oct 1.
Prolonged wear of facial protective equipment can lead to occupational dermatoses.
To identify important causes of occupational dermatoses from facial protective equipment.
A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed using PubMed and Embase databases. Articles were included if they reported occupational dermatoses caused by surgical/procedure masks or N95 respirators, or both.
We identified 344 articles, and 16 were suitable for inclusion in this review. Selected articles focused on facial occupational dermatoses in health care workers. Allergic contact dermatitis to the elastic straps, glue, and formaldehyde released from the mask fabric was reported. Irritant contact dermatitis was common on the cheeks and nasal bridge due to pressure and friction. Irritant dermatitis was associated with personal history of atopic dermatitis and prolonged mask wear (>6 hours). Acneiform eruption was reported due to prolonged wear and occlusion. Contact urticaria was rare.
Only publications listed in PubMed or Embase were included. Most publications were case reports and retrospective studies.
This systematic review from members of the American Contact Dermatitis Society highlights cases of occupational dermatitis to facial protective equipment, including potential offending allergens. This work may help in the diagnosis and treatment of health care workers with facial occupational dermatitis.
长时间佩戴面部防护设备可导致职业性皮肤病。
确定面部防护设备导致职业性皮肤病的重要原因。
按照系统评价与Meta分析的首选报告项目指南，使用PubMed和Embase数据库进行系统评价。若文章报道了由外科手术/操作口罩或N95呼吸器或两者引起的职业性皮肤病，则纳入研究。
我们共检索到344篇文章，其中16篇适合纳入本综述。入选文章主要关注医护人员的面部职业性皮肤病。报道了对面罩弹性带、胶水以及面罩织物释放的甲醛的过敏性接触性皮炎。由于压力和摩擦，刺激性接触性皮炎在脸颊和鼻梁处较为常见。刺激性皮炎与特应性皮炎个人史以及长时间佩戴口罩（>6小时）有关。因长时间佩戴和闭塞作用报道了痤疮样皮疹。接触性荨麻疹较为罕见。
仅纳入了PubMed或Embase中列出的出版物。大多数出版物为病例报告和回顾性研究。
美国接触性皮炎学会成员进行的这项系统评价强调了面部防护设备导致职业性皮炎的病例，包括潜在的致敏变应原。这项工作可能有助于对面部职业性皮炎医护人员的诊断和治疗。
