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[正常分娩:生理分娩支持与医疗程序。法国国家卫生管理局(HAS)在法国妇产科医师学会(CNGOF)和法国助产士学院(CNSF)合作下制定的指南——分娩期间何时以及如何采取医疗行动?]

[Normal childbirth: physiologic labor support and medical procedures. Guidelines of the French National Authority for Health (HAS) with the collaboration of the French College of Gynaecologists and Obstetricians (CNGOF) and the French College of Midwives (CNSF) - - When and how to take medical action during labor?].

作者信息

Lejeune-Sadaa V, Mattuizzi A, Sentilhes L

机构信息

Service de gynécologie-obstétrique, centre hospitalier d'Auch, allée Marie-Clarac, 32008 Auch, France.

Service de gynécologie-obstétrique, CHU de Bordeaux, 33000 Bordeaux, France.

出版信息

Gynecol Obstet Fertil Senol. 2020 Dec;48(12):917-930. doi: 10.1016/j.gofs.2020.09.017. Epub 2020 Oct 2.

Abstract

OBJECTIVE

The aim of this chapter is to provide recommendations for good practice regarding drug and technical interventions that may be considered during normal delivery.

METHODS

These recommendations were established by an expert consensus based on an analysis of the scientific literature and the French and international recommendations available on the subject.

RESULTS

Interventions during latent phase of the first stage of labor (up to 5-6cm) must be performed according to the fetal and maternal contraction tolerance (consensus agreement). In the active phase (from 5-6cm to full dilatation), dilation speed under 1cm/4h between 5 and 7cm or under 1cm/2h beyond 7cm is considered abnormal, it is then recommended to propose: an amniotomy if the membranes are intact and administration of oxytocin if membranes are already ruptured and uterine contractions are considered insufficient (consensus agreement). Intravenous (IV) antibiotic prophylaxis (at least four hours before birth) is recommended during labor in women at risk for group B streptococcal (GBS) maternofetal infection (GBS vaginal portage or GBS bacteriuria during pregnancy or history of maternofetal GBS infection) (grade B). In case of rupture of membranes after 37weeks of gestation without spontaneous labor, it is recommended: if the patient has GBS, to begin antibiotic prophylaxis immediately (consensus agreement); if delivery did not occur after 12hours, to start antibiotic prophylaxis (grade A), to set up dedicated patient monitoring (consensus agreement), to screen for an infection (at least a full blood count, a vaginal sample and a dipstick test) (consensus agreement). It is recommended not to start expulsive efforts as soon as a complete dilation is identified but to let the fetal presentation go down (grade A). The administration of oxytocin is recommended if the patient does not feel inclined to push and the presentation has not reached low-pelvic station after two hours of complete dilation in case of insufficient uterine activity (AE). There is no argument for recommending a push technique over another (grade B). It is recommended to inform the gynecologist-obstetrician in case of non-progression of the fetus after two hours of complete dilation with sufficient uterine activity (AE). Prophylactic administration of oxytocin at 5 or 10 IU is recommended to prevent postpartum hemorrhage after vaginal delivery (grade A). Administration could be performed intravenously (slow injection over about a minute) or intramuscularly (AE). In case of placental retention, manual removal of the placenta is recommended (grade A). In absence of bleeding, it must be performed after 30mins after birth, without exceeding 60mins (AE).

CONCLUSION

These recommendations define indications and methods for drug and technical interventions during a normal delivery to prevent poor obstetrical outcomes.

摘要

目的

本章旨在为正常分娩过程中可能考虑的药物和技术干预提供良好实践建议。

方法

这些建议是通过专家共识制定的,基于对科学文献以及该主题的法国和国际建议的分析。

结果

第一产程潜伏期(直至5 - 6厘米)的干预必须根据胎儿和母体对宫缩的耐受情况进行(共识意见)。在活跃期(从5 - 6厘米至完全扩张),5至7厘米之间扩张速度低于1厘米/4小时或7厘米以上低于1厘米/2小时被视为异常,此时建议:若胎膜完整则行人工破膜,若胎膜已破且子宫收缩被认为不足则给予缩宫素(共识意见)。对于有B族链球菌(GBS)母婴感染风险的产妇(GBS阴道携带或孕期GBS菌尿或有母婴GBS感染史),建议在分娩期间进行静脉抗生素预防(至少在分娩前四小时)(B级)。妊娠37周后胎膜破裂且无自然分娩发动时,建议:若患者有GBS,立即开始抗生素预防(共识意见);若12小时后仍未分娩,开始抗生素预防(A级),建立专门的患者监测(共识意见),进行感染筛查(至少全血细胞计数、阴道样本和试纸检测)(共识意见)。建议在确认完全扩张后不要立即开始用力,而是让胎儿先下降(A级)。若子宫活动不足,在完全扩张两小时后患者仍无用力意愿且胎先露未达骨盆低位时,建议给予缩宫素(AE)。对于推荐某种用力技巧而非另一种技巧并无依据(B级)。在完全扩张两小时且子宫活动充分但胎儿无进展时,建议告知妇产科医生(AE)。建议预防性给予5或10国际单位的缩宫素以预防阴道分娩后的产后出血(A级)。给药可通过静脉注射(约一分钟缓慢注射)或肌肉注射(AE)。若胎盘滞留,建议人工剥离胎盘(A级)。在无出血情况下,必须在分娩后30分钟后进行,且不超过60分钟(AE)。

结论

这些建议明确了正常分娩期间药物和技术干预的适应证及方法,以预防不良产科结局。

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