Division of Pediatric Cardiology, University of Michigan, Ann Arbor, MI, USA48109.
Division of Pediatric Hematology and Oncology, University of Michigan, Ann Arbor, MI, USA48109.
Cardiol Young. 2020 Dec;30(12):1973-1975. doi: 10.1017/S1047951120003182. Epub 2020 Oct 5.
Lymphatic vessel dysplasia is associated with Fontan-associated protein-losing enteropathy. Extra nodal non-Hodgkin lymphomas including mucosa-associated lymphoid tissue (MALT lymphoma) are associated with lymphatic vessel dysplasia. Here, we describe the case of a 7-year-old with Fontan-associated protein-losing enteropathy who developed MALT lymphoma with a clinical course indicative of interaction between these pathologies and improvement in protein-losing enteropathy after MALT lymphoma treatment. This case suggests a pathophysiologic overlap which has implications for the management of Fontan-associated protein-losing enteropathy.
淋巴血管发育不良与法乐四联症相关蛋白丢失性肠病相关。结外非霍奇金淋巴瘤包括黏膜相关淋巴组织（MALT 淋巴瘤）与淋巴血管发育不良相关。在此，我们描述了一例 7 岁法乐四联症相关蛋白丢失性肠病患儿，其发展为 MALT 淋巴瘤，临床表现提示这些病理之间存在相互作用，并且在 MALT 淋巴瘤治疗后蛋白丢失性肠病得到改善。该病例提示了一种病理生理学重叠，这对法乐四联症相关蛋白丢失性肠病的治疗具有重要意义。
