Henry Ford Hospital, 2799 West Grand Boulevard, Suite K7, Detroit, MI 48202, USA.
Henry Ford Hospital, 2799 West Grand Boulevard, Suite K7, Detroit, MI 48202, USA.
Clin Liver Dis. 2020 Nov;24(4):535-547. doi: 10.1016/j.cld.2020.06.001. Epub 2020 Aug 16.
Hepatocellular carcinoma is among the leading causes of morbidity and mortality. Owing to the current epidemic of metabolic syndrome, the population affected by nonalcoholic fatty liver disease/nonalcoholic steatohepatitis continues to increase and now comprises a significant portion with those with hepatocellular carcinoma. The World Health Organization goal of obtaining universal hepatitis B virus vaccination has led to a global effort to improve vaccination, prevent mother-to-child transmission, and implement linkage to care to avoid the development of hepatocellular carcinoma. In contrast with the decreased burden of chronic hepatitis C virus, there has been an increase in new-onset acute hepatitis C virus.
肝细胞癌是导致发病率和死亡率的主要原因之一。由于目前代谢综合征的流行，非酒精性脂肪性肝病/非酒精性脂肪性肝炎的患者数量不断增加，其中相当一部分人患有肝细胞癌。世界卫生组织获得乙型肝炎病毒普遍疫苗接种的目标促使全球努力改善疫苗接种、预防母婴传播，并实施关联治疗以避免肝细胞癌的发展。与慢性丙型肝炎病毒负担的减少形成对比的是，新发丙型肝炎病毒感染有所增加。
