Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island.
Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island; Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island; Center of Innovation in Long-Term Services and Supports, Providence Veterans Affairs Medical Center, Providence, Rhode Island; Department of Pharmacy, Rhode Island Hospital, Providence, Rhode Island.
Am J Prev Med. 2020 Nov;59(5):e179-e188. doi: 10.1016/j.amepre.2020.05.009. Epub 2020 Oct 2.
Annual influenza vaccination is associated with reduced mortality among older adults and lower overall public health burden of influenza. This study seeks to identify the characteristics associated with repeat influenza vaccination and determine whether age-group (51-59, 60-69, ≥70 years) differences exist.
Using the nationally representative, longitudinal Health and Retirement Study waves 2004, 2008, 2012, and 2016, adults aged >50 years were followed from 2004 to 2016. In 2020, age-stratified, multinomial regression models were estimated to identify the factors associated with respondents receiving the vaccine repeatedly (every time point), occasionally (some years), or never, with censoring for death.
The overall proportion of adults repeatedly receiving influenza vaccine monotonically increased across age groups from 25.9% among adults aged 51-59 years to 62.4% among those aged ≥70 years. Black, non-Hispanics and smokers were less likely to repeatedly receive an influenza vaccine than white, non-Hispanics and nonsmokers (RR=0.40-0.61 and RR=0.60-0.75, respectively, p<0.05 for all). Those who had 1‒4 medical doctor visits in the past 2 years (RR=1.60-2.99) or cholesterol screening (RR=2.67-3.48) in the past 2 years were significantly more likely to repeatedly receive influenza vaccine than those who had none.
Although adults aged 60-69 years and ≥70 years are more likely to receive influenza vaccine repeatedly than adults aged 51-59 years, age-specific interventions for repeat influenza vaccination may not be as effective as interventions targeted to certain subgroups among adults aged ≥51 years.
每年接种流感疫苗可降低老年人的死亡率,并降低流感对总体公共卫生的负担。本研究旨在确定与重复接种流感疫苗相关的特征,并确定是否存在年龄组(51-59 岁、60-69 岁、≥70 岁)差异。
使用具有全国代表性的纵向健康与退休研究(Health and Retirement Study)2004 年、2008 年、2012 年和 2016 年的波次数据,对年龄>50 岁的成年人进行随访,随访时间从 2004 年到 2016 年。2020 年,按年龄分层,采用多项回归模型来确定与受访者重复(每个时间点)、偶尔(某些年份)或从未接种流感疫苗相关的因素,并对死亡进行了删失。
在年龄组中,重复接种流感疫苗的成年人比例总体呈单调递增趋势,从 51-59 岁成年人的 25.9%增加到≥70 岁成年人的 62.4%。与非西班牙裔白种人相比,非西班牙裔黑人和吸烟者重复接种流感疫苗的可能性较低(RR=0.40-0.61 和 RR=0.60-0.75,均<0.05)。在过去 2 年中,有 1-4 次就诊医生(RR=1.60-2.99)或胆固醇筛查(RR=2.67-3.48)的成年人比无就诊医生或胆固醇筛查的成年人更有可能重复接种流感疫苗。
尽管 60-69 岁和≥70 岁的成年人比 51-59 岁的成年人更有可能重复接种流感疫苗,但针对≥51 岁成年人特定年龄组的重复接种流感疫苗的干预措施可能不如针对特定亚组成年人的干预措施有效。