Department of immunization, Xuhui District Centre for Disease Control and Prevention, Shanghai, China.
Department of public health, The Tianlin Community Health Service Centre in Xuhui District, Shanghai, China.
Hum Vaccin Immunother. 2024 Dec 31;20(1):2364480. doi: 10.1080/21645515.2024.2364480. Epub 2024 Jul 7.
Elderly individuals face a high risk of hospitalization and death related to influenza, thus prioritizing them for influenza vaccination. Due to variations in the influenza virus and waning protective antibodies, annual influenza vaccination is recommended. However, research on repeated influenza vaccination among elderly individuals in China is limited. From 2020 to 2022, the average influenza vaccination coverage among registered elderly individuals in Shanghai was 4.1%, showing a declining trend over time. In 2020, the rate of repeated influenza vaccination among elderly individuals was 28.35%, which rose to almost two-thirds both in 2021 and 2022. No increased risk of adverse events following immunization was observed after repeated influenza vaccination during this period. Our study also found that elderly individuals with Shanghai household registration, managed by community clinics, and older age tended to receive more doses of repeated influenza vaccination throughout the period from 2020 to 2022. Increasing influenza vaccine coverage among elderly individuals in Shanghai is both urgent and challenging. Health authorities should intensify educational and promotional campaigns to encourage uptake of annual repeated influenza vaccination among elderly individuals.
老年人因流感而住院和死亡的风险较高，因此应优先接种流感疫苗。由于流感病毒的变异和保护性抗体的衰减，建议每年接种流感疫苗。然而，中国针对老年人重复接种流感疫苗的研究有限。2020 年至 2022 年，上海登记老年人的平均流感疫苗接种率为 4.1%，呈逐年下降趋势。2020 年，老年人重复接种流感疫苗的比例为 28.35%，2021 年和 2022 年这一比例几乎翻了一番。在此期间，重复接种流感疫苗后并未观察到免疫接种后不良事件的风险增加。我们的研究还发现，在 2020 年至 2022 年期间，具有上海户籍、由社区诊所管理且年龄较大的老年人更倾向于接受更多剂次的重复流感疫苗接种。提高上海老年人的流感疫苗接种率既紧迫又具有挑战性。卫生部门应加强教育和宣传活动，鼓励老年人每年重复接种流感疫苗。
