CHV Frégis, 43 Av Aristide Briand, 94110 Arcueil, France.
Can Vet J. 2020 Oct;61(10):1049-1054.
A 5-year-old intact male Gascon Saintongeois dog was presented with a 6-month history of coughing, laryngeal paralysis, a deglutition disorder of gradual onset, and left-sided Horner's syndrome. The dog was admitted as an emergency for acute central vestibular signs. Magnetic resonance images identified a left extra-axial brainstem lesion extending caudally from the medulla to the vagosympathetic trunk. Histological and immunohistological examination revealed a high grade epithelioid malignant peripheral nerve sheath tumor (MPNST). This case report is the first description of a MPNST of the vagus nerve compressing the brainstem and causing multiple cranial nerve dysfunction in a dog. Key clinical message: Nerve sheath tumors have been reported in many locations arising from spinal nerve roots and cranial nerves. Although the trigeminal nerve is the most commonly affected nerve, other cranial nerves such as the vagus can be affected.
一只 5 岁的雄性 Gascon Saintongeois 犬，完整未绝育，出现咳嗽、喉麻痹、进行性吞咽障碍和左侧霍纳氏综合征，病程 6 个月。因急性中枢性前庭体征而被紧急收治入院。磁共振成像发现延髓至迷走交感干的左侧脑外轴索病变。组织学和免疫组织化学检查显示高级别上皮样恶性外周神经鞘瘤（MPNST）。本病例报告是首例描述犬的迷走神经 MPNST 压迫脑干并导致多颅神经功能障碍的病例。关键临床信息：神经鞘瘤已在许多部位报道，起源于脊神经根和颅神经。虽然三叉神经最常受影响，但其他颅神经如迷走神经也可能受到影响。
