From AniCura I Portoni Rossi Veterinary Hospital, Zola Predosa, Italy (R.B., L.B., F.B., J.A., M.B.).
From Universita' degli Studi di Perugia, Perugia, Italy (M.T.M.).
J Am Anim Hosp Assoc. 2022 May 1;58(3):137-140. doi: 10.5326/JAAHA-MS-7243.
A 4 yr old male Maltese dog presented with a 1 wk history of intermittent neck pain and progressive difficulty walking. Neurologic evaluation was consistent with a left-sided brainstem lesion. On oral examination, left lingual hemiatrophy was evident suggesting hypoglossal nerve involvement. A dumbbell-shaped extra-axial mass in the left side of the caudal fossa extending extracranially through the hypoglossal canal was detected by MRI. At postmortem histologic examination, the hypoglossal nerve was diffusely infiltrated by fusiform neoplastic cells arranged in Antoni A and Antoni B patterns. This is the first description of a malignant nerve sheath tumor selectively involving the hypoglossal nerve in a dog.
一只 4 岁雄性马耳他犬，表现为间歇性颈部疼痛和进行性行走困难，病史 1 周。神经学评估与左侧脑干病变一致。口腔检查时，左侧舌半侧萎缩明显，提示舌下神经受累。MRI 显示颅后窝左侧哑铃形硬膜外肿块向颅外延伸通过舌下神经管。尸检组织学检查发现，舌下神经被梭形肿瘤细胞弥漫浸润，呈 Antoni A 和 Antoni B 型排列。这是首例犬选择性累及舌下神经的恶性神经鞘瘤的描述。
