Chaurasia Rachna, Jain Anshul, Sengar Narendra Singh, Pandey Shivali
Department of Radiodiagnosis, Maharani Laxmi Bai Medical College, Jhansi, India.
Department of Anaesthesiology, Maharani Laxmi Bai Medical College, Jhansi, India.
J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):166-171. doi: 10.4103/joacp.JOACP_343_17. Epub 2020 Jun 15.
Ultrasound is a safe and non-invasive method for detecting numerous pathologies. Pediatric patients are often uncooperative which leads to decreased quality and increased time of scan. We compared the conventional means alone and combination of oral midazolam for the above cited purpose.
This double blind prospective study (CTRI/2016/06/007030) was conducted after obtaining due approval from institutional ethical committee. One hundred Children aged 2-6 years belonging to ASA class 1 or 2, posted for high resolution ultrasonography of abdomen were included in the study. They were randomised to receive midazolam 0.3 mg/kg mixed in 20 mL of apple juice (Group I) or 20 mL of apple juice alone (Group II) 20 minutes prior to the procedure. The parameters assessed were level of cooperation, sonologist's satisfaction, total scan time, heart rate and SpO.
Out of 100 patients, 44 patients of group I and 42 of group II were analysed. The cooperation score was significantly higher in Group I (35%) than Group II (19%). Likert scale revealed very satisfied and satisfied rating in 61.3% (Group I) and 21.4% (Group II). The time taken by sonologist and number of attempts were significantly less in Group I than Group II. There was no difference in discharge time between the groups. There was no reportable adverse event in either group.
Oral midazolam is a safe and effective agent to aid routine abdominal ultrasonography in pediatric patients.
超声是一种检测多种病变的安全且非侵入性的方法。儿科患者常常不配合，这会导致扫描质量下降以及扫描时间增加。为了上述目的，我们比较了单纯的传统方法与口服咪达唑仑的联合应用。
本双盲前瞻性研究（CTRI/2016/06/007030）在获得机构伦理委员会的适当批准后进行。纳入100名年龄在2至6岁、ASA分级为1或2级、计划进行腹部高分辨率超声检查的儿童。在检查前20分钟，他们被随机分为两组，一组接受将0.3 mg/kg咪达唑仑混入20 mL苹果汁中的溶液（第一组），另一组仅接受20 mL苹果汁（第二组）。评估的参数包括合作程度、超声科医生的满意度、总扫描时间、心率和血氧饱和度。
100名患者中，分析了第一组的44名患者和第二组的42名患者。第一组的合作评分（35%）显著高于第二组（19%）。李克特量表显示，第一组中有61.3%的患者评分为非常满意和满意，第二组中这一比例为21.4%。第一组超声科医生花费的时间和尝试次数显著少于第二组。两组之间的出院时间没有差异。两组均未报告不良事件。
口服咪达唑仑是辅助儿科患者进行常规腹部超声检查的一种安全有效的药物。
