Tavassoli-Hojjati Sara, Mehran Majid, Haghgoo Roza, Tohid-Rahbari Monireh, Ahmadi Rahil
Pediatric Dentistry Department, Dental School, Shahed University , Tehran, Iran.
Iran J Pediatr. 2014 Apr;24(2):198-206.
Providing a safe and efficient dental treatment for a young patient is a challenge for the dentist and the child. The purpose of this study was to investigate the effectiveness, safety and acceptability of buccal midazolam in dental pediatric patients and to compare it with oral Midazolam.
Eighteen uncooperative healthy children aged 2.5-6 years were randomized to each of buccal midazolam (0.3mg/kg) or oral midazolam (0.5mg/kg) at the first visit, the alternative has been used at the second visit in a cross-over manner. The study took place at pediatric dentistry clinic of Shahed University, Tehran, from November 2011 to June 2012. The patients' vital signs and behavioral scores were recorded. The patient, the operator and the observer were blinded to the applied medication. Post operatively, patients' and parents' satisfaction were assessed by Visual Analogue Score and a questionnaire respectively. The P-value was set at 0.05 for significance level.
There were no significant differences in physiologic factors in the medication groups at time 0, 10, 20, 30 minutes and discharge. There was also no significant difference between the two groups in behavioral parameters. The majority of parents rated both sedative agents as "effective" or "very effective" and their children mostly were without anxiety or with minor anxiety.
Buccal midazolam may be safely and efficiently used in sedation of pediatric dental patients.
为年轻患者提供安全有效的牙科治疗对牙医和儿童来说都是一项挑战。本研究的目的是调查颊部咪达唑仑在牙科儿科患者中的有效性、安全性和可接受性，并将其与口服咪达唑仑进行比较。
18名年龄在2.5至6岁之间不合作的健康儿童在首次就诊时被随机分为颊部咪达唑仑（0.3mg/kg）组或口服咪达唑仑（0.5mg/kg）组，在第二次就诊时以交叉方式使用另一种药物。该研究于2011年11月至2012年6月在德黑兰沙希德大学的儿科牙科诊所进行。记录患者的生命体征和行为评分。患者、操作人员和观察者对所使用的药物不知情。术后，分别通过视觉模拟评分法和问卷对患者和家长的满意度进行评估。显著性水平的P值设定为0.05。
在0、10、20、30分钟及出院时，用药组的生理因素无显著差异。两组在行为参数方面也无显著差异。大多数家长将两种镇静剂评为“有效”或“非常有效”，他们的孩子大多没有焦虑或只有轻微焦虑。
颊部咪达唑仑可安全有效地用于儿科牙科患者的镇静。
