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高压氧医学在放射性骨坏死和放疗后伤口治疗中的作用:机构经验

Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience.

作者信息

Korambayil Pradeoth Mukundan, Ambookan Prashanth Varkey, Pillai Sreekumar, Karangath Rameela Ravindran, George Deepak

机构信息

Jubilee Institute of Surgery for Hand, Aesthetic & Microsurgery, Department of Plastic Surgery & Burns, Jubilee Mission Medical College and Research Institute, Bishop Alapatt Road, Thrissur, Kerala India.

Department of Computer, St. Thomas College (Autonomous), Bishop Alapatt Road, Thrissur, Kerala India.

出版信息

Indian J Surg Oncol. 2020 Sep;11(3):469-474. doi: 10.1007/s13193-020-01128-0. Epub 2020 Jun 15.

Abstract

To study the effectiveness of hyperbaric medicine in osteoradionecrosis and irradiation induced wounds. To evolve a protocol for management with combined surgical modality for irradiation induced injury. This study was carried out in the Plastic Surgery Department, from November 2011 to December 2018. A total of 30 patients with post irradiation patients subjected to hyperbaric oxygen therapy during the management were enrolled in the study. The results regarding the changes in wound and complications were noted. Out of 30 patients, 20 patients were with radiation injury involving the oral cavity, one patient with left lower limb, one with breast, 3 with radiation injury of cheek, 3 of mandible, one with radiation cystitis and one involving the tooth socket. One patient experienced reversible myopia as a complication of hyperbaric therapy. No other complications were noted. Hyperbaric therapy is a useful adjunct for surgery in management of osteoradionecrosis and post irradiation wound and proves therapeutic in some post irradiated wound where we cannot offer surgical correction.

摘要

研究高压氧医学在放射性骨坏死和放射性损伤创面治疗中的有效性。制定一种联合手术方式治疗放射性损伤的方案。本研究于2011年11月至2018年12月在整形外科进行。共有30例放疗后患者在治疗期间接受了高压氧治疗并纳入研究。记录伤口变化及并发症情况。30例患者中,20例有口腔放射性损伤,1例左下肢放射性损伤,1例乳房放射性损伤,3例面颊放射性损伤,3例下颌骨放射性损伤,1例放射性膀胱炎,1例牙槽窝放射性损伤。1例患者出现可逆性近视作为高压氧治疗的并发症。未发现其他并发症。高压氧治疗是手术治疗放射性骨坏死和放疗后创面的有用辅助手段,在一些无法进行手术矫正的放疗后创面中证明具有治疗作用。

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