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头颈部癌患者烟草消费复发情况的横断面研究

Relapse of Tobacco Consumption in Patients Treated for Head and Neck Cancer: a Cross Sectional Study.

作者信息

Naresh Jangir, Shruti Khemka, Amit Bhondve, Akash Singh, Vinay Venkatramanu, Ajay Vidyarthi, Mitali Dandekar

机构信息

Department of Surgical Oncology, Mahavir Cancer Sansthan, Patna, India.

Mahavir Cancer Sansthan, Patna, India.

出版信息

Indian J Surg Oncol. 2020 Sep;11(3):492-497. doi: 10.1007/s13193-020-01148-w. Epub 2020 Jul 20.

Abstract

Head and neck cancers are a major healthcare burden in the Indian Subcontinent mainly due to tobacco consumption. While advances in treatment have resulted in better control rates and survival, relapse of tobacco consumption contributes to recurrences. The authors embarked upon a cross-sectional questionnaire-based study to assess the burden of tobacco relapse along with factors resulting into relapse. Patients on follow-up after treatment of tobacco-related head and neck cancers in a dedicated cancer institute were included in the study. Demographic data was noted, and responses were obtained on a five-point Likert's scale for reasons of relapse which were analyzed with a median and interquartile range. Predictors of relapse were assessed using multivariate logistic regression analysis. In our sample size of 500, relapse rate was 15%, majority of which occurred in the first year of follow-up when disease was loco-regionally controlled. Most common causative factor for relapse was lower motivation to quit. Care givers must incorporate tobacco cessation counseling as an integral part of head and neck cancer treatment.

摘要

头颈癌是印度次大陆主要的医疗负担,主要原因是烟草消费。虽然治疗方面的进展已带来更好的控制率和生存率,但烟草消费的复发导致了疾病的复发。作者开展了一项基于问卷调查的横断面研究,以评估烟草复发的负担以及导致复发的因素。在一家专门的癌症研究所接受与烟草相关的头颈癌治疗后进行随访的患者被纳入该研究。记录了人口统计学数据,并就复发原因采用五点李克特量表获取了回答,这些回答采用中位数和四分位间距进行分析。使用多变量逻辑回归分析评估复发的预测因素。在我们500人的样本量中,复发率为15%,其中大部分发生在随访的第一年,此时疾病处于局部区域控制状态。复发最常见的致病因素是戒烟动力较低。护理人员必须将戒烟咨询纳入头颈癌治疗的一个组成部分。

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本文引用的文献

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Treating Nicotine Dependence and Preventing Smoking Relapse in Cancer Patients.治疗癌症患者的尼古丁依赖并预防吸烟复发
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Laryngoscope. 1997 Jul;107(7):888-92. doi: 10.1097/00005537-199707000-00010.

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