Biological Rhythm Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Government of India, Imphal, India.
Distributed Information Sub-centre, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Government of India, Imphal, India.
Front Endocrinol (Lausanne). 2020 Sep 10;11:622. doi: 10.3389/fendo.2020.00622. eCollection 2020.
The origin of the coronavirus disease 2019 (COVID-19) pandemic is zoonotic. The circadian day-night is the rhythmic clue to organisms for their synchronized body functions. The "development for mankind" escalated the use of artificial light at night (ALAN). In this article, we tried to focus on the possible influence of this anthropogenic factor in human coronavirus (HCoV) outbreak. The relationship between the occurrences of coronavirus and the ascending curve of the night-light has also been delivered. The ALAN influences the physiology and behavior of bat, a known nocturnal natural reservoir of many . The "threatened" and "endangered" status of the majority of bat species is mainly because of the destruction of their proper habit and habitat predominantly through artificial illumination. The stress exerted by ALAN leads to the impaired body functions, especially endocrine, immune, genomic integration, and overall rhythm features of different physiological variables and behaviors in nocturnal animals. Night-light disturbs "virus-host" synchronization and may lead to mutation in the genomic part of the virus and excessive virus shedding. We also proposed some future strategies to mitigate the repercussions of ALAN and for the protection of the living system in the earth as well.
2019 年冠状病毒病(COVID-19)大流行的起源是动物源性的。昼夜节律是生物体同步身体功能的节奏线索。“为人类谋发展”加剧了夜间人工照明(ALAN)的使用。在本文中,我们试图关注这种人为因素对人类冠状病毒(HCoV)爆发的可能影响。冠状病毒的发生与夜间灯光上升曲线之间的关系也已经交付。ALAN 影响蝙蝠的生理和行为,蝙蝠是许多的已知夜间自然宿主。大多数蝙蝠物种处于“受威胁”和“濒危”状态,主要是因为它们的适当习惯和栖息地被破坏,主要是通过人工照明。ALAN 施加的压力导致身体功能受损,特别是内分泌、免疫、基因组整合以及夜间动物不同生理变量和行为的整体节律特征。夜间灯光扰乱了“病毒-宿主”的同步性,可能导致病毒基因组部分发生突变和病毒过度脱落。我们还提出了一些未来的策略来减轻 ALAN 的影响,并保护地球上的生命系统。