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急性主动脉夹层手术后急性肺栓塞的管理

Management of acute pulmonary embolism after acute aortic dissection surgery.

作者信息

Nakamura Ken, Orii Kouan, Hanai Makoto, Abe Takayuki, Haida Hirofumi

机构信息

Department of Cardiac Surgery, Saitama Cardiovascular and Respiratory Center, Kumagaya-shi, Saitama, Japan.

出版信息

J Cardiol Cases. 2020 Aug 3;22(4):195-197. doi: 10.1016/j.jccase.2020.06.010. eCollection 2020 Oct.

DOI:10.1016/j.jccase.2020.06.010
PMID:33014204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7520534/
Abstract

Acute aortic dissection (AAD) continues to be associated with high mortality and morbidity. Pulmonary embolism is also a life-threatening disease. The treatment of these life-threatening diseases remains controversial in case complications arise. Thrombolytic therapy and intensive treatment would be needed to manage these fatal diseases. A 49-year-old man with progressive back pain was admitted to our hospital. Computed tomography (CT) scan revealed type A AAD. Emergency operation for hemiarch replacement was performed. Two weeks postoperatively, the patient's oxygenation worsened and his d-dimer levels elevated. CT scan revealed a massive thrombus in the bilateral pulmonary arteries. Intensive anticoagulation therapy was started immediately. On postoperative day 27, the patient was weaned from mechanical ventilation, but the false lumen with thrombus was recanalized again. The patient was discharged on postoperative day 75 without resulting in major complications for aortic dissection. The diagnosis of pulmonary embolism concomitant with AAD is difficult. The treatment of pulmonary embolism after AAD is controversial. Our strategy seems to be suitable for acute pulmonary embolism that occurs during the treatment of AAD. ˂ The diagnosis of pulmonary embolism concomitant with acute aortic dissection (AAD) is difficult. The treatment of pulmonary embolism after AAD is controversial. Investigating factor XIII levels might help in the early detection of pulmonary embolism.>.

摘要

急性主动脉夹层(AAD)仍然与高死亡率和高发病率相关。肺栓塞也是一种危及生命的疾病。如果出现并发症,这些危及生命疾病的治疗仍存在争议。治疗这些致命疾病需要溶栓治疗和强化治疗。一名49岁渐进性背痛男性入住我院。计算机断层扫描(CT)显示为A型AAD。进行了半弓置换急诊手术。术后两周,患者氧合恶化,D-二聚体水平升高。CT扫描显示双侧肺动脉有大量血栓。立即开始强化抗凝治疗。术后第27天,患者脱机,但有血栓的假腔再次再通。患者术后第75天出院,未出现主动脉夹层的主要并发症。诊断AAD合并肺栓塞很困难。AAD后肺栓塞的治疗存在争议。我们的策略似乎适用于AAD治疗期间发生的急性肺栓塞。<诊断急性主动脉夹层(AAD)合并肺栓塞很困难。AAD后肺栓塞的治疗存在争议。检测因子XIII水平可能有助于早期发现肺栓塞。>

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/c0efa4073f39/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/ee8587266ffc/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/f09f2bf624ad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/c0efa4073f39/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/ee8587266ffc/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/f09f2bf624ad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d54/7520534/c0efa4073f39/gr3.jpg

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本文引用的文献

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Comparison of surgical and conservative treatment outcomes for type a aortic dissection in elderly patients.老年患者A型主动脉夹层手术治疗与保守治疗效果的比较。
J Cardiothorac Surg. 2018 Dec 18;13(1):129. doi: 10.1186/s13019-018-0814-6.
2
Consumption coagulopathy in acute aortic dissection: principles of management.急性主动脉夹层中的消耗性凝血病:治疗原则
J Cardiothorac Surg. 2017 Jun 12;12(1):50. doi: 10.1186/s13019-017-0613-5.
3
Combined measurement of factor XIII and D-dimer is helpful for differential diagnosis in patients with suspected pulmonary embolism.
联合检测凝血因子 XIII 和 D - 二聚体有助于疑似肺栓塞患者的鉴别诊断。
Clin Chem Lab Med. 2017 Oct 26;55(12):1948-1953. doi: 10.1515/cclm-2017-0072.
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Medicine (Baltimore). 2016 Sep;95(36):e4710. doi: 10.1097/MD.0000000000004710.
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Ann Thorac Surg. 2016 Mar;101(3):945-51. doi: 10.1016/j.athoracsur.2015.08.047. Epub 2015 Oct 23.
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