Ando Takashi, Kobayashi Toshiya, Endo Hitoshi, Nagata Tokuichiro, Ono Hirokuni, Suzuki Takamaro, Murakami Hiroshi, Chikada Masahide, Makuuchi Haruo
Department of Cardiovascular Surgery, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
Ann Vasc Dis. 2012;5(4):428-34. doi: 10.3400/avd.oa.12.00021. Epub 2012 Oct 31.
Optimum treatment for acute aortic dissection (AAD) with a thrombosed false lumen (thrombosed AAD) remains controversial. We evaluated the outcome of thrombosed AAD according to treatment strategy.
We examined 280 patients with AAD, of which 30 had thrombosed AAD. We compared computed tomography findings, cardiac performance, and clinical course in 28 of these patients. Patients were divided into three groups for the comparison: Group E (emergency surgery), Group C (conservative therapy), and Group S (conservative therapy switched to emergency surgery).
In Group E (n = 13), one patient died and 12 survived. In Group C (n = 10), all patients were discharged, of which two died of cancer and two of the remaining eight survivors underwent subsequent elective surgery. In Group S (n = 5), one patient died and four survived following surgery.
It was hard to predict re-dissection or rupture following conservative treatment for thrombosed AAD. Basically, we should perform emergency surgery following the diagnosis of thrombosed AAD, particularly in complicated cases such as those with pericardial effusion, tamponade, and large aorta. Conservative therapy has a very limited application in patients with the initial stages of thrombosed AAD.
对于伴有血栓形成的假腔的急性主动脉夹层(AAD,即血栓形成性AAD)的最佳治疗方法仍存在争议。我们根据治疗策略评估了血栓形成性AAD的治疗结果。
我们检查了280例AAD患者,其中30例为血栓形成性AAD。我们比较了其中28例患者的计算机断层扫描结果、心脏功能和临床病程。为进行比较,将患者分为三组:E组(急诊手术)、C组(保守治疗)和S组(保守治疗转为急诊手术)。
E组(n = 13)中,1例患者死亡,12例存活。C组(n = 10)中,所有患者均出院,其中2例死于癌症,其余8例存活者中有2例随后接受了择期手术。S组(n = 5)中,1例患者术后死亡,4例存活。
对于血栓形成性AAD进行保守治疗后,很难预测是否会再次发生夹层或破裂。基本上,在诊断为血栓形成性AAD后应进行急诊手术,尤其是在伴有心包积液、心脏压塞和主动脉粗大等复杂病例中。保守治疗在血栓形成性AAD初始阶段的患者中的应用非常有限。