Breda Giovanni Luis, Domino Natália Ramos, de Noronha Lucia, Duarte Dos Santos Claudia N, Zanluca Camila, Kruger Rodrigo Sfredo, Queiroz-Telles Flávio, Raboni Sonia Mara
Complexo Hospital de Clínicas, Universidade Federal Do Paraná, 180 General Carneiro Street, Curitiba, 80060-900, Brazil.
Instituto Carlos Chagas/Fiocruz PR, 3775 Professor Algacyr Munhoz Mader Street, Curitiba, 81310-020, Brazil.
Med Mycol Case Rep. 2020 Sep 17;30:12-14. doi: 10.1016/j.mmcr.2020.09.002. eCollection 2020 Dec.
Invasive aspergillosis (IA) usually occurs in immunocompromised hosts, but in the last decade IA has emerged in critically ill non-neutropenic patients, as those with severe Influenza and Chronic Obstructive Pulmonary Disease (COPD). We report an unusual fatal case of disseminated IA in a non-immunocompromised patient following yellow fever vaccine-associated viscerotropic disease.
侵袭性曲霉病（IA）通常发生在免疫功能低下的宿主中，但在过去十年中，IA在重症非中性粒细胞减少患者中出现，如患有严重流感和慢性阻塞性肺疾病（COPD）的患者。我们报告了一例在黄热病疫苗相关的嗜内脏性疾病后发生的非免疫功能低下患者播散性IA的罕见致命病例。
