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一名无严重免疫功能低下的重症患者发生播散性肠侵袭性曲霉病。

Disseminated enteroinvasive aspergillosis in a critically ill patient without severe immunocompromise.

作者信息

Fieber Jennifer H, Atladóttir Jórunn, Solomon Daniel G, Maerz Linda L, Reddy Vikram, Mitchell-Richards Kisha, Longo Walter E

机构信息

Yale University School of Medicine MD Candidate, New Haven, CT, USA

Yale Department of Surgery, New Haven, CT, USA.

出版信息

J Surg Case Rep. 2013 Nov 4;2013(11):rjt091. doi: 10.1093/jscr/rjt091.

DOI:10.1093/jscr/rjt091
PMID:24968426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3853028/
Abstract

Invasive aspergillosis (IA) is a rapidly progressive and often fatal infectious disease described classically in patients who are highly immunocompromised. However, there has been increasing evidence that IA may affect critically ill patients without traditional risk factors. We present a case of a 47-year-old man without conventional risk factors for IA who presented with impending sepsis and proceeded to have a complicated hospital course with a postmortem diagnosis of invasive gastrointestinal aspergillosis of the small bowel.

摘要

侵袭性曲霉病（IA）是一种进展迅速且往往致命的传染病，传统上多见于免疫功能极度低下的患者。然而，越来越多的证据表明，IA可能会影响没有传统危险因素的重症患者。我们报告一例47岁男性病例，该患者没有患IA的传统危险因素，表现为即将发生脓毒症，随后经历了复杂的住院过程，尸检诊断为小肠侵袭性胃肠道曲霉病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/d0c53b7649db/rjt09105.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/cc7a68d40a93/rjt09101.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/ec06cf1d49ba/rjt09102.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/6f3f57e99a52/rjt09103.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/f28fd15ec135/rjt09104.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/d0c53b7649db/rjt09105.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/cc7a68d40a93/rjt09101.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/ec06cf1d49ba/rjt09102.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/6f3f57e99a52/rjt09103.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/f28fd15ec135/rjt09104.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/481d/3853028/d0c53b7649db/rjt09105.jpg

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本文引用的文献

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Clinical significance of extra-pulmonary involvement of invasive aspergillosis: a retrospective autopsy-based study of 107 patients.侵袭性曲霉病肺外受累的临床意义：一项基于107例患者尸检的回顾性研究
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